Results 81 to 90 of about 19,078,260 (300)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Comparative analysis of different biophysical techniques for exosome characterization

Scientific Reports
Exosomes, as key mediators of intercellular communication, have demonstrated great potential in drug delivery. However, their accurate characterization remains challenging due to their complex physical properties.
Xiaojuan Yu, Zhaoxing Wang, Ruifeng Zhang, Wenli Guo, Qing Chang, Wendan Chu, Chengshi Zeng, Lan Wang, Chuanfei Yu, Wenqi Li   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Cellular Strategies of Protein Quality Control [PDF]

Cold Spring Harbor Perspectives in Biology, 2011
Eukaryotic cells must contend with a continuous stream of misfolded proteins that compromise the cellular protein homeostasis balance and jeopardize cell viability. An elaborate network of molecular chaperones and protein degradation factors continually monitor and maintain the integrity of the proteome. Cellular protein quality control relies on three
Bryan, Chen, Marco, Retzlaff, Thomas, Roos, Judith, Frydman   +3 more
openaire   +2 more sources

Analysis of Data Quality and Information Quality Problems in Digital Manufacturing [PDF]

, 2008
 This work focuses on the increasing importance of data quality in organizations, especially in digital manufacturing companies. The paper firstly reviews related works in field of data quality, including definition, dimensions, measurement and ...
K. Q. Wang, B. Eynard, EYNARD, Benoit, ROUCOULES, Lionel, Tong, S, R, L. Roucoules, TONG, Shurong, Wang, K, Q, S. R. Tong, WANG, Keqin   +9 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Differential Scales of Protein Quality Control [PDF]

Cell, 2014
Proteins are notorious for their unpleasant behavior-continually at risk of misfolding, collecting damage, aggregating, and causing toxicity and disease. To counter these challenges, cells have evolved elaborate chaperone and quality control networks that can resolve damage at the level of the protein, organelle, cell, or tissue. On the smallest scale,
Wolff, Suzanne, Weissman, Jonathan S., Dillin, Andrew   +2 more
openaire   +2 more sources

DNA-based control of protein activity [PDF]

, 2016
DNA has emerged as a highly versatile construction material for nanometer-sized structures and sophisticated molecular machines and circuits. The successful application of nucleic acid based systems greatly relies on their ability to autonomously sense ...
Merkx, M., Engelen, W., Janssen, BMG Brian, Janssen, B.M.G., Engelen, W Wouter, Merkx, M Maarten   +5 more
core   +2 more sources

Practical Concepts of Quality Control [PDF]

, 2012
This book aims to provide a concise account of the essential elements of quality control. It is designed to be used as a text for courses on quality control for students of industrial engineering at the advanced undergraduate, or as a reference for ...

core   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source