Results 161 to 170 of about 31,021 (196)

A Review of Approaches to the Synthesis of DCL-Based Prostate-Specific Membrane Antigen Ligands. [PDF]

Int J Mol Sci
Zyk NY, Butakova NS, Machulkin AE, Beloglazkina EK.   +3 more
europepmc   +1 more source

Editorial: Unraveling enzyme-substrate dynamics in protein acylation and disease implications. [PDF]

Front Mol Biosci
Cheng S, Liu T, Xing J, Zhang G, Zhang L, Zhao W.   +5 more
europepmc   +1 more source

Deacylation of SNAP25 protein family isoforms reveals distinct substrate selectivities of α/β hydrolase domain (ABHD) deacylases

Mejuto L, Pipito L, Ng CP, Tomkinson NC, Reynolds CA, Deganutti G, Greaves J.   +6 more
europepmc   +1 more source

Dynamic S-acylation controls CMG2 maturation, extracellular matrix regulation, and anthrax toxin entry

Abrami L, Blaskovic S, Joliot O, Mercier V, Kunz B, Mesquita FS, van der Goot FG.   +6 more
europepmc   +1 more source

The molecular era of protein S-acylation: spotlight on structure, mechanisms, and dynamics [PDF]

Critical Reviews in Biochemistry and Molecular Biology, 2018
S-Acylation (commonly referred to as S-palmitoylation) is a post-translational modification consisting in the covalent attachment of an acyl chain to a cysteine residue of the target protein. The lability of the resulting thioester bond gives S-acylation an essential characteristic: its reversibility. S-acylation dynamically regulates different aspects
Maria Eugenia Zaballa, Gisou Van Der Goot   +1 more
exaly   +4 more sources

Site-specific analysis of protein S-acylation by resin-assisted capture [PDF]

Journal of Lipid Research, 2011
Protein S-acylation is a major posttranslational modification whereby a cysteine thiol is converted to a thioester. A prototype is S-palmitoylation (fatty acylation), in which a protein undergoes acylation with a hydrophobic 16 carbon lipid chain. Although this modification is a well-recognized determinant of protein function and localization, current ...
J Will Thompson, Martin Moseley, Rainbo Hultman   +2 more
exaly   +4 more sources