Results 71 to 80 of about 31,021 (196)

Functional characterization of the three Drosophila retinal degeneration C (RDGC) protein phosphatase isoforms. [PDF]

PLoS ONE, 2018
Drosophila retinal degeneration C (RDGC) is the founding member of the PPEF family of protein phosphatases. RDGC mediates dephosphorylation of the visual pigment rhodopsin and the TRP ion channel.
Olaf Voolstra, Lisa Strauch, Matthias Mayer, Armin Huber   +3 more
doaj   +1 more source

Determination of Protein S-Acylation State by Enhanced Acyl-Switch Methods [PDF]

, 2019
S-Acylation is increasingly being recognized as an important dynamic posttranslational modification of cysteine residues in proteins. Various approaches have been described for assaying protein S-acylation with acyl-switch approaches being the most common and accessible.
Hurst, Charlotte H., Turnbull, Dionne, Hemsley, Piers A.   +2 more
openaire   +3 more sources

Structure of infective Getah virus at 2.8 Å resolution determined by cryo-electron microscopy

Cell Discovery, 2022
Getah virus (GETV), a member of the genus alphavirus, is a mosquito-borne pathogen that can cause pyrexia and reproductive losses in animals. Although antibodies to GETV have been found in over 10% of healthy people, there are no reports of clinical ...
Aojie Wang, Feng Zhou, Congcong Liu, Dongsheng Gao, Ruxi Qi, Yiheng Yin, Sheng Liu, Yuanzhu Gao, Lutang Fu, Yinhe Xia, Yawei Xu, Chuanqing Wang, Zheng Liu   +12 more
doaj   +1 more source

Grain setting defect1 (GSD1) function in rice depends on S-acylation and interacts with actin 1 (OsACT1) at its C-terminal

Frontiers in Plant Science, 2015
Grain setting defect1 (GSD1), a plant-specific remorin protein specifically localized at the plasma membrane and plasmodesmata of phloem companion cells, affects grain setting in rice through regulating the transport of photoassimilates.
Jinshan eGui, Shuai eZheng, Junhui eShen, Laigeng eLi   +3 more
doaj   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

S-acylation of a non-secreted peptide controls plant immunity via secreted-peptide signal activation

EMBO Reports
Small peptides modulate multiple processes in plant cells, but their regulation by post-translational modification remains unclear. ROT4 (ROTUNDIFOLIA4) belongs to a family of Arabidopsis non-secreted small peptides, but knowledge on its molecular ...
Wenliang Li, Tushu Ye, Weixian Ye, Jieyi Liang, Wen Wang, Danlu Han, Xiaoshi Liu, Liting Huang, Youwei Ouyang, Jianwei Liao, Tongsheng Chen, Chengwei Yang, Jianbin Lai   +12 more
doaj   +1 more source

In vitro Detection of S-acylation on Recombinant Proteins via the Biotin-Switch Technique

Bio-Protocol, 2014
Protein palmitoylation is the post-translational modification of proteins via the attachment of palmitate through acyl linkages. The nucleophile sulfhydryl group of cysteines is the common palmitoylation site.
Dong Qi, Roger Innes
doaj   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source