Results 21 to 30 of about 6,974,231 (359)
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
mBio, 2022 Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial competition and virulence by secreting toxic effector proteins.
Timothy A. Klein +7 more
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Developing Gram-negative bacteria for the secretion of heterologous proteins
Microbial Cell Factories, 2018 Gram-negative bacteria are attractive hosts for recombinant protein production because they are fast growing, easy to manipulate, and genetically stable in large cultures. However, the utility of these microbes would expand if they also could secrete the
Lisa Ann Burdette +3 more
doaj +1 more source
PLoS Biology, 2019 Processes of molecular innovation require tinkering and shifting in the function of existing genes. How this occurs in terms of molecular evolution at long evolutionary scales remains poorly understood.
R. Denise, S. Abby, E. Rocha
semanticscholar +1 more source
Frontiers in Microbiology, 2021 Lactic acid bacteria (LAB) have been used as starter cultures and producers of enzymes, antimicrobial peptides or metabolites that contribute to the flavor, texture and safety of food products.
Anh-Minh Tran +8 more
doaj +1 more source
Protein secretion in streptomycetes [PDF]
FEMS Microbiology Letters, 2006 Some aspects of the current knowledge on protein secretion in streptomycetes are presented including recent data on the identification of genes in the general secretory pathway, on the importance of the signal peptide structure and on the number of ribosome-binding sites inside signal peptides which can influence the production level of a gene product.
R, Morosoli, F, Shareck, D, Kluepfel
openaire +2 more sources
The Evolutionarily Conserved Serine Residues in BRI1 LRR Motifs Are Critical for Protein Secretion
Frontiers in Plant Science, 2020 As a well-studied leucine-rich-repeat receptor-like kinases (LRR-RLKs) in Arabidopsis (Arabidopsis thaliana), BRI1 functions as a cell surface receptor for sensing the smallest ligand molecule identified thus far. The weak allele bri1-9 (S662F) harbors a
Tianshu Chen +7 more
doaj +1 more source
RAB6 and microtubules restrict protein secretion to focal adhesions
Journal of Cell Biology, 2019 Fourriere et al. demonstrate the existence of secretion hotspots juxtaposed to focal adhesions. Post-Golgi transport carriers use a subset of microtubules to reach focal adhesions.
L. Fourriere +9 more
semanticscholar +1 more source
Nature Communications, 2019 Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in response to
Mercè Carmona +8 more
doaj +1 more source
mBio, 2017 Sophisticated nanomachines are used by bacteria for protein secretion. In Gram-negative bacteria, the type 2 secretion system (T2SS) is composed of a pseudopilus assembly platform in the inner membrane and a secretin complex in the outer membrane.
Iain D. Hay +2 more
doaj +1 more source
Protein secretion: Puzzling receptors [PDF]
Current Biology, 1997 All known sorting receptors for soluble cargo in the secretory pathway are transmembrane proteins. For sorting to the regulated pathway, however, a subpopulation of secretory proteins, associated with the membrane but not membrane-spanning, appears to link cargo and membrane in storage granule biogenesis.
Thiele, Christoph +2 more
openaire +3 more sources