Results 11 to 20 of about 3,139,545 (345)
COMTOP: Protein Residue–Residue Contact Prediction through Mixed Integer Linear Optimization
Membranes, 2021 Protein contact prediction helps reconstruct the tertiary structure that greatly determines a protein’s function; therefore, contact prediction from the sequence is an important problem. Recently there has been exciting progress on this problem, but many
Md. Selim Reza +5 more
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Prediction of protein-protein interaction sites in intrinsically disordered proteins
Frontiers in Molecular Biosciences, 2022 Intrinsically disordered proteins (IDPs) participate in many biological processes by interacting with other proteins, including the regulation of transcription, translation, and the cell cycle.
Ranran Chen +10 more
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Marine Drugs, 2021 Alginate, a natural polysaccharide derived from brown seaweed, is finding multiple applications in biomedicine via its transformation through chemical, physical, and, increasingly, enzymatic processes.
Thi Nhu Thuong Nguyen +4 more
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Discovering the Ultimate Limits of Protein Secondary Structure Prediction
Biomolecules, 2021 Secondary structure prediction (SSP) of proteins is an important structural biology technique with many applications. There have been ~300 algorithms published in the past seven decades with fierce competition in accuracy.
Chia-Tzu Ho +4 more
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Entropic Landscape: the method to predict folding patterns and regional stability of proteins [PDF]
, 2009 I propose a new method to calculate the entropy of a given protein sequence fragment. The set of fragment entropies over all possible fragments of the given sequence shows which region of the sequence is statistically stable and which region has a strong
Kentaro Onizuka
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Frontiers in Microbiology, 2023 The epitope is the site where antigens and antibodies interact and is vital to understanding the immune system. Experimental identification of linear B-cell epitopes (BCEs) is expensive, is labor-consuming, and has a low throughput.
Yue Qi, Peijie Zheng, Guohua Huang
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An Alternative Model of Amino Acid Replacement [PDF]
, 2004 The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
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Frontiers in Genetics, 2022 Lysine glutarylation is a post-translational modification (PTM) that plays a regulatory role in various physiological and biological processes. Identifying glutarylated peptides using proteomic techniques is expensive and time-consuming.
Fatma Indriani +4 more
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Exploiting Sparse Statistics for a Sequence-Based Prediction of the Effect of Mutations
Algorithms, 2019 Recent work showed that there is a significant difference between the statistics of amino acid triplets and quadruplets in sequences of folded proteins and randomly generated sequences.
Mihaly Mezei
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Predicting the Disease Risk of Protein Mutation Sequences With Pre-training Model
Frontiers in Genetics, 2020 Accurately identifying the missense mutations is of great help to alleviate the loss of protein function and structural changes, which might greatly reduce the risk of disease for tumor suppressor genes (e.g., BRCA1 and PTEN). In this paper, we propose a
Kuan Li +4 more
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