Results 11 to 20 of about 6,753,180 (197)
Swaps in protein sequences [PDF]
Proteins: Structure, Function, and Bioinformatics, 2002 AbstractAn important question in protein evolution is to what extent proteins may have undergone swaps (switches of domain or fragment order) during evolution. Such events might have occurred in several forms: Swaps of short fragments, swaps of structural and functional motifs, or recombination of domains in multidomain proteins.
Amit, Fliess, Benny, Motro, Ron, Unger
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Global analysis of SNPs, proteins and protein-protein interactions: approaches for the prioritisation of candidate disease genes. [PDF]
, 2009 PhDUnderstanding the etiology of complex disease remains a challenge in biology. In recent years there has been an explosion in biological data, this study investigates machine learning and network analysis methods as tools to aid candidate disease ...
Dobson, Richard James Butler
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Prediction of protein-protein interaction sites in intrinsically disordered proteins
Frontiers in Molecular Biosciences, 2022 Intrinsically disordered proteins (IDPs) participate in many biological processes by interacting with other proteins, including the regulation of transcription, translation, and the cell cycle.
Ranran Chen +10 more
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Marine Drugs, 2021 Alginate, a natural polysaccharide derived from brown seaweed, is finding multiple applications in biomedicine via its transformation through chemical, physical, and, increasingly, enzymatic processes.
Thi Nhu Thuong Nguyen +4 more
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Exploring Protein Sequence Space Using Computationally Directed Recombination [PDF]
, 2006 Evolution has provided us with many protein sequences. However, these sequences represent a very small fraction of the possible sequences. In the laboratory, scientists have explored areas of sequence space not represented by natural proteins both to ...
Meyer, Michelle Margaret
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Bayesian sequence learning for predicting protein cleavage points [PDF]
, 2005 A challenging problem in data mining is the application of efficient techniques to automatically annotate the vast databases of biological sequence data.
Michael Mayo, Mayo, Michael
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Discovering the Ultimate Limits of Protein Secondary Structure Prediction
Biomolecules, 2021 Secondary structure prediction (SSP) of proteins is an important structural biology technique with many applications. There have been ~300 algorithms published in the past seven decades with fierce competition in accuracy.
Chia-Tzu Ho +4 more
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Non-Contiguous Protein Recombination [PDF]
, 2013 Swapping sequence elements among related proteins can produce chimeric proteins with novel behaviors and improved properties such as enhanced stability. Although homologous mutations are much more conservative than random mutations, chimeras of distantly-
Smith, Matthew Alexander
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Comparison of DNA Sequences with Protein Sequences
Genomics, 1997 The FASTA package of sequence comparison programs has been expanded to include FASTX and FASTY, which compare a DNA sequence to a protein sequence database, translating the DNA sequence in three frames and aligning the translated DNA sequence to each sequence in the protein database, allowing gaps and frameshifts.
W R, Pearson +3 more
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Frontiers in Microbiology, 2023 The epitope is the site where antigens and antibodies interact and is vital to understanding the immune system. Experimental identification of linear B-cell epitopes (BCEs) is expensive, is labor-consuming, and has a low throughput.
Yue Qi, Peijie Zheng, Guohua Huang
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