Results 21 to 30 of about 3,139,545 (345)
EvolveAGene 3: A DNA coding sequence evolution simulation program [PDF]
, 2007 EvolveAGene 3 is a realistic coding sequence simulation program that separates mutation from selection and allows the user to set selection conditions, including variable regions of selection intensity within the sequence and variation in intensity of ...
Barry G. Hall
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Comparison of DNA Sequences with Protein Sequences
Genomics, 1997 The FASTA package of sequence comparison programs has been expanded to include FASTX and FASTY, which compare a DNA sequence to a protein sequence database, translating the DNA sequence in three frames and aligning the translated DNA sequence to each sequence in the protein database, allowing gaps and frameshifts.
W R, Pearson +3 more
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IEEE Access, 2019 RNA-binding hot spots are a small and complementary set of interfacial residues that contribute most to the binding energy of protein-RNA interfaces. As experimental methods for identifying hot spots are time-consuming, labor-intensive and costly, there ...
Sijia Zhang, Le Zhao, Junfeng Xia
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Molecular cloning and expression of novel fibroblast growth factor-2 conjugated with immunodominant domains of pseudomonas exotoxin [PDF]
, 2015 Angiogenesis is very important in cancer growth and metastasis. Basic fibroblast growth factor (bFGF) as one of the most important angiogenesis factors is an attractive target for cancer vaccine.
Farazmandfar, T. +6 more
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Protein sequence randomness and sequence/structure correlations
Biophysical Journal, 1995 We investigated protein sequence/structure correlation by constructing a space of protein sequences, based on methods developed previously for constructing a space of protein structures. The space is constructed by using a representation of the amino acids as vectors of 10 property factors that encode almost all of their physical properties.
Rahman, R.S., Rackovsky, S.
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Data mining of protein families using common peptides [PDF]
, 2008 Predicting the function of a protein from its sequence is typically addressed using sequence-similarity. Here we propose a motif-based approach, using supervised motif extraction from protein sequences belonging to one functional family.
Assaf Gottlieb, David Horn, Uri Weingart
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Translation conditional models for protein coding sequences [PDF]
, 2000 A coding sequence is defined as a DNA sequence coding the primary structure of a protein (a polypeptide). Such a sequence must satisfy a specific constraint, which consists in coding a functional protein, As the genetic code is degenerated, there exists,
Mathé, Catherine, Rodolphe, François
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Frontiers in Bioengineering and Biotechnology, 2020 New anticancer agents are continually needed because cancerous cells continue to evolve resistance to the currently available chemotherapeutic agents.
Lamiaa A. Al-Madboly +5 more
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Wei2GO: weighted sequence similarity-based protein function prediction [PDF]
PeerJ, 2022 Background Protein function prediction is an important part of bioinformatics and genomics studies. There are many different predictors available, however most of these are in the form of web-servers instead of open-source locally installable versions ...
Maarten J.M.F. Reijnders
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Structural analysis of DNA binding by C.Csp231I, a member of a novel class of R-M controller proteins regulating gene expression [PDF]
, 2015 In a wide variety of bacterial restriction–modification systems, a regulatory `controller' protein (or C-protein) is required for effective transcription of its own gene and for transcription of the endonuclease gene found on the same operon.
Kneale, G. G. +5 more
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