Results 71 to 80 of about 6,753,180 (197)
The scale-free nature of protein sequence space. [PDF]
PLoS ONE, 2018 The sequence space of five protein superfamilies was investigated by constructing sequence networks. The nodes represent individual sequences, and two nodes are connected by an edge if the global sequence identity of two sequences exceeds a threshold ...
Patrick C F Buchholz +2 more
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What makes a protein sequence a prion? [PDF]
PLoS Computational Biology, 2015 Typical amyloid diseases such as Alzheimer's and Parkinson's were thought to exclusively result from de novo aggregation, but recently it was shown that amyloids formed in one cell can cross-seed aggregation in other cells, following a prion-like ...
Raimon Sabate +3 more
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Multiple sequence alignment with the Divide-and-Conquer method. [PDF]
, 1998 Stoye J. Multiple sequence alignment with the Divide-and-Conquer method. Gene. 1998;211(2):GC45-GC56.An improved algorithm for the simultaneous alignment of multiple protein and nucleic acid sequences, the Divide-and-Conquer Alignment procedure (DCA), is
Jens Stoye +1 more
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Species-specific protein sequence and fold optimizations
BMC Bioinformatics, 2002 Background An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its kind, we sought to identify and exploit the amino-acid signatures that make ...
Michalickova Katerina +2 more
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In silico study of Bacillus spB201 amylase through protein sequence inspection
Journal of the Arab Society for Medical ResearchBackground/aim Bioinformatics is the automatic processing of biological information, and it is a helpful tool to study the structure-function relationship of various proteins.
Sameh Ben Mabrouk +3 more
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MESSA: MEta-Server for protein Sequence Analysis
BMC Biology, 2012 Background Computational sequence analysis, that is, prediction of local sequence properties, homologs, spatial structure and function from the sequence of a protein, offers an efficient way to obtain needed information about proteins under study.
Cong Qian, Grishin Nick V
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FPGA-based protein sequence alignment : A review
EPJ Web of Conferences, 2017 Sequence alignment have been optimized using several techniques in order to accelerate the computation time to obtain the optimal score by implementing DP-based algorithm into hardware such as FPGA-based platform.
Md. Isa Mohd. Nazrin +7 more
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Sequence determinants of protein aggregation: tools to increase protein solubility
Microbial Cell Factories, 2005 Escherichia coli is one of the most widely used hosts for the production of recombinant proteins. However, very often the target protein accumulates into insoluble aggregates in a misfolded and biologically inactive form.
Ventura Salvador
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Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses [PDF]
, 2004 Zöllner FG. Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses. Bielefeld (Germany): Bielefeld University; 2004.Für das Verständnis von biologischen Funktionen können Proteindockingverfahren ...
Frank G. Zöllner +1 more
core
, 2009 Immune evasion by Plasmodium falciparum is favored by extensive allelic diversity of surface antigens. Some of them, most notably the vaccine-candidate merozoite surface protein (MSP)-1, exhibit a poorly understood pattern of allelic dimorphism, in which
Roy, Scott W +9 more
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