Results 171 to 180 of about 4,957,023 (387)

Assessment of in silico protein sequence analysis in the clinical classification of variants in cancer risk genes. [PDF]

J Community Genet, 2017
Kerr ID, Cox HC, Moyes K, Evans B, Burdett BC, van Kan A, McElroy H, Vail PJ, Brown KL, Sumampong DB, Monteferrante NJ, Hardman KL, Theisen A, Mundt E, Wenstrup RJ, Eggington JM.   +15 more
europepmc   +1 more source

Genome Sequence of the Thermotolerant Foodborne Pathogen Salmonella enterica Serovar Senftenberg ATCC 43845 and Phylogenetic Analysis of Loci Encoding Increased Protein Quality Control Mechanisms [PDF]

, 2017
Scott V. Nguyen, Gregory P. Harhay, James L. Bono, Timothy P. L. Smith, Dayna M. Harhay   +4 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Front-End Electron Transfer Dissociation Coupled to a 21 Tesla FT-ICR Mass Spectrometer for Intact Protein Sequence Analysis. [PDF]

J Am Soc Mass Spectrom, 2017
Weisbrod CR, Kaiser NK, Syka JEP, Early L, Mullen C, Dunyach JJ, English AM, Anderson LC, Blakney GT, Shabanowitz J, Hendrickson CL, Marshall AG, Hunt DF.   +12 more
europepmc   +1 more source

Identification of DNA-binding protein target sequences by physical effective energy functions, free energy analysis of lambda repressor-DNA complexes [PDF]

, 2007
Elisabetta Moroni, Michele Caselle, Federico Fogolari   +2 more
openalex   +1 more source

The Phyre2 web portal for protein modeling, prediction and analysis

Nature Protocols, 2015
L. Kelley, Stefans Mezulis, C. M. Yates, Mark N. Wass, M. Sternberg   +4 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Phylogenetic analysis of new Iranian Fig badnavirus-1 isolates based on their movement protein gene sequence

, 2017
Athar Alishiri, Farshad Rakhshandehroo, Gholamreza Salehi, Masood Shamsbakhsh   +3 more
openalex   +2 more sources

mPUMA: a computational approach to microbiota analysis by de novo assembly of operational taxonomic units based on protein-coding barcode sequences [PDF]

, 2013
Matthew G. Links, Bonnie Chaban, Sean M. Hemmingsen, Kevin Muirhead, Janet E. Hill   +4 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source