Results 21 to 30 of about 4,957,023 (387)

Expression of goat RNA binding protein (NANOS2), development and evaluation of anti-NANOS2 IgY antibodies

Czech Journal of Animal Science, 2015
Available rabbit anti-NANOS2 antibodies failed to recognize the NANOS2 protein of goat origin though they showed better reactivity towards the same protein of human and mice origin.
X. Yao, H. Ren, W. Yang, T. Diraviyam, F. Tang, M. Yu, J. Hua, X. Zhang, S. Peng   +8 more
doaj   +1 more source

BEAST: Bayesian evolutionary analysis by sampling trees [PDF]

, 2007
Background The evolutionary analysis of molecular sequence variation is a statistical enterprise. This is reflected in the increased use of probabilistic models for phylogenetic inference, multiple sequence alignment, and molecular population genetics ...
Drummond, Alexei J., Rambaut, Andrew
core   +3 more sources

MMseqs2: sensitive protein sequence searching for the analysis of massive data sets

bioRxiv, 2017
Sequencing costs have dropped much faster than Moore's law in the past decade, and sensitive sequence searching has become the main bottleneck in the analysis of large (meta)genomic datasets. While previous methods sacrificed sensitivity for speed gains,
Martin Steinegger, J. Söding
semanticscholar   +1 more source

HCMV Envelope Glycoprotein Diversity Demystified

Frontiers in Microbiology, 2019
Human cytomegalovirus (HCMV) is the leading viral cause of congenital birth defects and is responsible for morbidity and mortality in immunosuppressed individuals.
Mathilde Foglierini, Mathilde Foglierini, Jessica Marcandalli, Laurent Perez   +3 more
doaj   +1 more source

Adenovirus type 5 E4 Orf3 protein targets promyelocytic leukaemia (PML) protein nuclear domains for disruption via a sequence in PML isoform II that is predicted as a protein interaction site by bioinformatic analysis [PDF]

, 2009
Human adenovirus type 5 infection causes the disruption of structures in the cell nucleus termed promyelocytic leukaemia (PML) protein nuclear domains or ND10, which contain the PML protein as a critical component. This disruption is achieved through the
Araujo, Beech, Bernardi, Bernardi, Borden, Bourhis, Callaghan, Carvalho, Condemine, Condemine, Dalessio, Doucas, E. Emmott, Evans, Everett, Everett, Everett, Fagioli, Fagioli, Hoppe, Ishov, Janderova-Rossmeislova, Jensen, K. N. Leppard, Kalderon, Kelly, Liu, M. S. Cortese, Mohan, Nevels, Peng, Romero, Salomoni, Scaglioni, Shen, Sternsdorf, Stracker, T. Rich   +37 more
core   +1 more source

Designing hardware for protein sequence analysis [PDF]

Bioinformatics, 2003
Abstract We present the architecture of PROSIDIS, a special purpose co-processor designed to search for the occurrence of substrings similar to a given ‘template string’ within a proteome. Actual tests show speed up figures ranging from 5 to 50 with respect to conventional general-purpose processors.
Marongiu, Alessandro, Palazzari, Paolo, Rosato, Vittorio   +2 more
openaire   +3 more sources

Using sound to understand protein sequence data: new sonification algorithms for protein sequences and multiple sequence alignments

BMC Bioinformatics, 2021
Background The use of sound to represent sequence data—sonification—has great potential as an alternative and complement to visual representation, exploiting features of human psychoacoustic intuitions to convey nuance more effectively.
Edward J. Martin, Thomas R. Meagher, Daniel Barker   +2 more
doaj   +1 more source

Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450 [PDF]

, 2006
Creating artificial protein families affords new opportunities to explore the determinants of structure and biological function free from many of the constraints of natural selection.
Arnold, Frances H., Bloom, Jesse D., Endelman, Jeffrey B., Hiraga, Kaori, Landwehr, Marco, Otey, Christopher R.   +5 more
core   +1 more source

iLearn : an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data

Briefings Bioinform., 2019
With the explosive growth of biological sequences generated in the post-genomic era, one of the most challenging problems in bioinformatics and computational biology is to computationally characterize sequences, structures and functions in an efficient ...
Zhen Chen, Pei Zhao, Fuyi Li, T. Marquez-Lago, A. Leier, Jerico Revote, Yan Zhu, D. Powell, T. Akutsu, Geoffrey I. Webb, K. Chou, Alexander Ian Smith, R. Daly, Jian Li, Jiangning Song   +14 more
semanticscholar   +1 more source

Density Peak clustering of protein sequences associated to a Pfam clan reveals clear similarities and interesting differences with respect to manual family annotation

BMC Bioinformatics, 2021
Background The identification of protein families is of outstanding practical importance for in silico protein annotation and is at the basis of several bioinformatic resources.
Elena Tea Russo, Alessandro Laio, Marco Punta   +2 more
doaj   +1 more source