Results 21 to 30 of about 5,259,649 (407)

A sequence embedding method for enzyme optimal condition analysis

BMC Bioinformatics, 2020
Background An enzyme activity is influenced by the external environment. It is important to have an enzyme remain high activity in a specific condition.
Xiangjun Li, Zhixin Dou, Yuqing Sun, Lushan Wang, Bin Gong, Lin Wan   +5 more
doaj   +1 more source

Using sound to understand protein sequence data: new sonification algorithms for protein sequences and multiple sequence alignments

BMC Bioinformatics, 2021
Background The use of sound to represent sequence data—sonification—has great potential as an alternative and complement to visual representation, exploiting features of human psychoacoustic intuitions to convey nuance more effectively.
Edward J. Martin, Thomas R. Meagher, Daniel Barker   +2 more
doaj   +1 more source

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry.

Proceedings of the National Academy of Sciences of the United States of America, 2004
Peptide sequence analysis using a combination of gas-phase ion/ion chemistry and tandem mass spectrometry (MS/MS) is demonstrated. Singly charged anthracene anions transfer an electron to multiply protonated peptides in a radio frequency quadrupole ...
J. Syka, J. Coon, M. Schroeder, J. Shabanowitz, D. Hunt   +4 more
semanticscholar   +1 more source

Designing hardware for protein sequence analysis [PDF]

Bioinformatics, 2003
Abstract We present the architecture of PROSIDIS, a special purpose co-processor designed to search for the occurrence of substrings similar to a given ‘template string’ within a proteome. Actual tests show speed up figures ranging from 5 to 50 with respect to conventional general-purpose processors.
Marongiu, Alessandro, Palazzari, Paolo, Rosato, Vittorio   +2 more
openaire   +4 more sources

Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1 [PDF]

, 1994
A gene (X33) localized on human chromosome 1 has been detected by crossreaction of its fusion protein with a monospecific antiserum directed against human vitamin-D-binding protein (hDBP; group-specific component).
Chirgwin, Church, Estaller, Feinberg, Hoffmann, Johnson, Kozak, Manley, McLeod, Meissner, Proudfood, Proudfood, Prunier, Sambrook, Sanger, Sheets, Smith, Tabor, Yanisch-Perron   +18 more
core   +1 more source

MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets

Nature Biotechnology, 2017
VOLUME 35 NUMBER 11 NOVEMBER 2017 NATURE BIOTECHNOLOGY performance was to combine the doublematch criterion with making k-mers as long as possible, which required finding similar and not just exact k-mers. This effectively bases our decision on up to 2 ×
Martin Steinegger, J. Söding
semanticscholar   +1 more source

Improved mass spectrometry compatibility is afforded by ammoniacal silver staining [PDF]

, 2006
Sequence coverage in MS analysis of protein digestion-derived peptides is a key issue for detailed characterization of proteins or identification at low quantities.
Berggren, Eschenbruch, Gevaert, Gharahdaghi, Granier, Hochstrasser, Lamanda, Neuhoff, Patton, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Richert, Schagger, Scheler, Shevchenko, Sinha, Tastet, Wiederkehr   +19 more
core   +3 more sources

HCMV Envelope Glycoprotein Diversity Demystified

Frontiers in Microbiology, 2019
Human cytomegalovirus (HCMV) is the leading viral cause of congenital birth defects and is responsible for morbidity and mortality in immunosuppressed individuals.
Mathilde Foglierini, Mathilde Foglierini, Jessica Marcandalli, Laurent Perez   +3 more
doaj   +1 more source

MMseqs2: sensitive protein sequence searching for the analysis of massive data sets

bioRxiv, 2017
Sequencing costs have dropped much faster than Moore's law in the past decade, and sensitive sequence searching has become the main bottleneck in the analysis of large (meta)genomic datasets. While previous methods sacrificed sensitivity for speed gains,
Martin Steinegger, J. Söding
semanticscholar   +1 more source

Analysis of protein sequences [PDF]

Genome Biology, 2000
Several programs to predict sequence and structural features of a protein can be run simultaneously on the PredictProtein server.
openaire   +2 more sources