Results 71 to 80 of about 5,259,649 (407)
A Protein Sequence Analysis Hardware Accelerator Based on Divergences
International Journal of Reconfigurable Computing, 2012 The Viterbi algorithm is one of the most used dynamic programming algorithms for protein comparison and identification, based on hidden markov Models (HMMs).
Juan Fernando Eusse +3 more
doaj +1 more source
Protein Sequence Retrieval and Phylogenetic Analysis of Various α-amylase Producing Bacillus species [PDF]
International Journal Bioautomation, 2020 Due to advancements made in biotechnology, genetic manipulation and medium optimization has been possible and that has led to high yield in enzyme especially α-amylase with improvised properties that find its application suitably in detergent, laundry ...
Sonali Priyadarshini +2 more
doaj +1 more source
An integrated native mass spectrometry and top-down proteomics method that connects sequence to structure and function of macromolecular complexes. [PDF]
, 2018 Mass spectrometry (MS) has become a crucial technique for the analysis of protein complexes. Native MS has traditionally examined protein subunit arrangements, while proteomics MS has focused on sequence identification.
Campuzano, Iain DG +4 more
core +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
The EVcouplings Python framework for coevolutionary sequence analysis
bioRxiv, 2018 Summary Coevolutionary sequence analysis has become a commonly used technique for de novo prediction of the structure and function of proteins, RNA, and protein complexes.
Thomas A. Hopf +15 more
semanticscholar +1 more source
PDBFlex: exploring flexibility in protein structures. [PDF]
, 2015 The PDBFlex database, available freely and with no login requirements at http://pdbflex.org, provides information on flexibility of protein structures as revealed by the analysis of variations between depositions of different structural models of the ...
Godzik, Adam +5 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Predicting the Specificity- Determining Positions of Receptor Tyrosine Kinase Axl
Frontiers in Molecular Biosciences, 2021 Owing to its clinical significance, modulation of functionally relevant amino acids in protein-protein complexes has attracted a great deal of attention.
Tülay Karakulak +8 more
doaj +1 more source
PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments
Nucleic Acids Res., 2006 PAL2NAL is a web server that constructs a multiple codon alignment from the corresponding aligned protein sequences. Such codon alignments can be used to evaluate the type and rate of nucleotide substitutions in coding DNA for a wide range of ...
M. Suyama, D. Torrents, P. Bork
semanticscholar +1 more source
AlignmentViewer: Sequence Analysis of Large Protein Families [PDF]
F1000Research, 2020 AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space.
Rob Sheridan +11 more
openaire +4 more sources