Results 41 to 50 of about 1,817,592 (311)
Secondary structure determines protein topology [PDF]
Protein Science, 2006 AbstractUsing a test set of 13 small, compact proteins, we demonstrate that a remarkably simple protocol can capture native topology from secondary structure information alone, in the absence of long‐range interactions. It has been a long‐standing open question whether such information is sufficient to determine a protein's fold.
George D. Rose +2 more
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International Journal of Food Properties, 2022 Fish protein hydrolyzates (FPH) are breakdown products of hydrolysis and are gaining importance in the field of nutraceuticals and functional foods due to their bioactive properties, high nutritional value, solubility, and digestibility. This study aimed
Undiganalu Gangadharappa Yathisha +2 more
doaj +1 more source
VarSite: Disease variants and protein structure
Protein Science, 2019 VarSite is a web server mapping known disease‐associated variants from UniProt and ClinVar, together with natural variants from gnomAD, onto protein 3D structures in the Protein Data Bank.
R. Laskowski +4 more
semanticscholar +1 more source
Multistage Combination Classifier Augmented Model for Protein Secondary Structure Prediction
Frontiers in Genetics, 2022 In the field of bioinformatics, understanding protein secondary structure is very important for exploring diseases and finding new treatments. Considering that the physical experiment-based protein secondary structure prediction methods are time ...
Xu Zhang +6 more
doaj +1 more source
A physical basis for protein secondary structure [PDF]
Proceedings of the National Academy of Sciences, 1999 A physical theory of protein secondary structure is proposed and tested by performing exceedingly simple Monte Carlo simulations. In essence, secondary structure propensities are predominantly a consequence of two competing local effects, one favoring hydrogen bond formation in helices and turns, the other opposing the attendant reduction in sidechain ...
George D. Rose, Rajgopal Srinivasan
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BCL::Score--knowledge based energy potentials for ranking protein models represented by idealized secondary structure elements. [PDF]
PLoS ONE, 2012 The topology of most experimentally determined protein domains is defined by the relative arrangement of secondary structure elements, i.e. α-helices and β-strands, which make up 50-70% of the sequence.
Nils Woetzel +5 more
doaj +1 more source
Prediction of protein secondary structure content [PDF]
Protein Engineering, Design and Selection, 1999 All existing algorithms for predicting the content of protein secondary structure elements have been based on the conventional amino-acid-composition, where no sequence coupling effects are taken into account. In this article, an algorithm was developed for predicting the content of protein secondary structure elements that was based on a new amino ...
Wei-min Liu, Kou-Chen Chou
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MASSP3: A System for Predicting Protein Secondary Structure
EURASIP Journal on Advances in Signal Processing, 2006 A system that resorts to multiple experts for dealing with the problem of predicting secondary structures is described, whose performances are comparable to those obtained by other state-of-the-art predictors.
Armano Giuliano +2 more
doaj +1 more source
Combining protein evolution and secondary structure [PDF]
Molecular Biology and Evolution, 1996 An evolutionary model that combines protein secondary structure and amino acid replacement is introduced. It allows likelihood analysis of aligned protein sequences and does not require the underlying secondary (or tertiary) structures of these sequences to be known.
Jeffrey L. Thorne +2 more
openaire +3 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source