Results 61 to 70 of about 13,913,476 (302)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Protein-RNA interactions: a structural analysis [PDF]
, 2001 A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Daley, DT +9 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
CSI-LSTM: A Web Server to Predict Protein Secondary Structure Using Bidirectional Long Short Term Memory and NMR Chemical Shifts [PDF]
, 2021 The description and understanding of protein structure rely on secondary structure heavily. Secondary structure determination and prediction are widely used in protein structure related research.
Conggang, Li +9 more
core +2 more sources
Molecules, 2018 This study aimed to investigate the variation of molecular functional properties of peanut protein isolate (PPI) over the storage process and reveal the correlation between the PPI secondary structure and properties in the storage procedure.
Xiaotong Sun +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structural characterisation of pre-processed thermoplastic protein derived from bloodmeal [PDF]
, 2012 Additives are required to convert bloodmeal powder into an extrudable thermoplastic protein-based bioplastic. These include a protein denaturant, a surfactant, a reducing agent and plasticisers.
Verbeek, Casparus Johan R. +2 more
core
Prediction of Protein Function Using Statistically Significant Sub-Structure Discovery [PDF]
, 2007 Proteins perform a vast number of functional roles. The number of protein structures available for analysis continues to grow and, with the development of methods to predict protein structure directly from genetic sequence without imaging technology, the
Lucas, Craig
core +4 more sources
Prediction of chaperonin GroE substrates using small structural patterns of proteins
FEBS Open Bio, 2023 Molecular chaperones are indispensable proteins that assist the folding of aggregation‐prone proteins into their functional native states, thereby maintaining organized cellular systems.
Shintaro Minami +5 more
doaj +1 more source
Deep learning for protein secondary structure prediction: Pre and post-AlphaFold
Computational and Structural Biotechnology Journal, 2022 This paper aims to provide a comprehensive review of the trends and challenges of deep neural networks for protein secondary structure prediction (PSSP). In recent years, deep neural networks have become the primary method for protein secondary structure
Dewi Pramudi Ismi +2 more
doaj +1 more source