Results 61 to 70 of about 1,631,863 (295)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
wiley +1 more source
MASSP3: A System for Predicting Protein Secondary Structure
EURASIP Journal on Advances in Signal Processing, 2006 A system that resorts to multiple experts for dealing with the problem of predicting secondary structures is described, whose performances are comparable to those obtained by other state-of-the-art predictors.
Armano Giuliano +2 more
doaj +1 more source
Secondary structure specific simpler prediction models for protein backbone angles
BMC Bioinformatics, 2022 Motivation Protein backbone angle prediction has achieved significant accuracy improvement with the development of deep learning methods. Usually the same deep learning model is used in making prediction for all residues regardless of the categories of ...
M. A. Hakim Newton +3 more
doaj +1 more source
DSC: public domain protein secondary structure prediction [PDF]
Bioinformatics, 1997 1. DSC has high accuracy. It has a prediction accuracy of 70.1% (per residue) on a standard set of 126 proteins. This percentage was confirmed by the recent CASP2 blind prediction challenge (see below). 2. DSC is based on simple linear statistics. Existing highaccuracy prediction methods are 'black-box' predictors based on complex non-linear statistics
King, Ross D. +3 more
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Improved Chou-Fasman method for protein secondary structure prediction
BMC Bioinformatics, 2006 Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj +1 more source
Properties and origins of protein secondary structure [PDF]
Physical Review E, 1994 12 pages (+4 figures, included in a single postscript file), LaTeX + RevTeX 3 ...
Socci, Nicholas D. +2 more
openaire +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Combining Coarse-Grained Protein Models with Replica-Exchange All-Atom Molecular Dynamics [PDF]
, 2013 We describe a combination of all-atom simulations with CABS, a well-established coarse-grained protein modeling tool, into a single multiscale protocol. The simulation method has been tested on the C-terminal beta hairpin of protein G, a model system of ...
Gront, Dominik +4 more
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source