Results 41 to 50 of about 986,500 (268)

The Molecular Properties of Peanut Protein: Impact of Temperature, Relative Humidity and Vacuum Packaging during Storage

open access: yesMolecules, 2018
This study aimed to investigate the variation of molecular functional properties of peanut protein isolate (PPI) over the storage process and reveal the correlation between the PPI secondary structure and properties in the storage procedure.
Xiaotong Sun   +5 more
doaj   +1 more source

Secondary structure specific simpler prediction models for protein backbone angles

open access: yesBMC Bioinformatics, 2022
Motivation Protein backbone angle prediction has achieved significant accuracy improvement with the development of deep learning methods. Usually the same deep learning model is used in making prediction for all residues regardless of the categories of ...
M. A. Hakim Newton   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Protein Secondary Structure Affects Glycan Clustering in Native Mass Spectrometry

open access: yesLife, 2021
Infection by the human noroviruses (hNoV), for the vast majority of strains, requires attachment of the viral capsid to histo blood group antigens (HBGAs).
Hao Yan   +8 more
doaj   +1 more source

Secondary structure determines protein topology [PDF]

open access: yesProtein Science, 2006
AbstractUsing a test set of 13 small, compact proteins, we demonstrate that a remarkably simple protocol can capture native topology from secondary structure information alone, in the absence of long‐range interactions. It has been a long‐standing open question whether such information is sufficient to determine a protein's fold.
Patrick J, Fleming   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Improved Chou-Fasman method for protein secondary structure prediction

open access: yesBMC Bioinformatics, 2006
Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj   +1 more source

Improved probability graph model for protein secondary structure prediction

open access: yesJournal of Hebei University of Science and Technology, 2016
Protein secondary structure is closely related to protein tertiary structure and function, and became a hot topic in bioinformatics. The probability graph model HMM (Hidden Markov model) is an important tool in this field.
Lingqi ZHAO   +4 more
doaj   +1 more source

Bayesian model of protein primary sequence for secondary structure prediction. [PDF]

open access: yesPLoS ONE, 2014
Determining the primary structure (i.e., amino acid sequence) of a protein has become cheaper, faster, and more accurate. Higher order protein structure provides insight into a protein's function in the cell. Understanding a protein's secondary structure
Qiwei Li   +4 more
doaj   +1 more source

A physical basis for protein secondary structure [PDF]

open access: yesProceedings of the National Academy of Sciences, 1999
A physical theory of protein secondary structure is proposed and tested by performing exceedingly simple Monte Carlo simulations. In essence, secondary structure propensities are predominantly a consequence of two competing local effects, one favoring hydrogen bond formation in helices and turns, the other opposing the attendant reduction in sidechain ...
R, Srinivasan, G D, Rose
openaire   +2 more sources

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