Results 61 to 70 of about 1,817,592 (311)

Protein Secondary Structure Prediction With a Reductive Deep Learning Method

Frontiers in Bioengineering and Biotechnology, 2021
Protein secondary structures have been identified as the links in the physical processes of primary sequences, typically random coils, folding into functional tertiary structures that enable proteins to involve a variety of biological events in life ...
Zhiliang Lyu, Zhijin Wang, Fangfang Luo, Jianwei Shuai, Jianwei Shuai, Yandong Huang   +5 more
doaj   +1 more source

DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data

Nucleic Acids Res., 2004
The DICHROWEB web server enables on-line analyses of circular dichroism (CD) spectroscopic data, providing calculated secondary structure content and graphical analyses comparing calculated structures and experimental data. The server is located at http:/
L. Whitmore, B. Wallace
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Secondary structure specific simpler prediction models for protein backbone angles

BMC Bioinformatics, 2022
Motivation Protein backbone angle prediction has achieved significant accuracy improvement with the development of deep learning methods. Usually the same deep learning model is used in making prediction for all residues regardless of the categories of ...
M. A. Hakim Newton, Fereshteh Mataeimoghadam, Rianon Zaman, Abdul Sattar   +3 more
doaj   +1 more source

Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection

Light: Science & Applications, 2017
Plasmonic nanoantennas offer new applications in mid-infrared (mid-IR) absorption spectroscopy with ultrasensitive detection of structural signatures of biomolecules, such as proteins, due to their strong resonant near-fields.
D. Etezadi, John B Warner IV, F. Ruggeri, G. Dietler, H. Lashuel, H. Altug   +5 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

The Molecular Properties of Peanut Protein: Impact of Temperature, Relative Humidity and Vacuum Packaging during Storage

Molecules, 2018
This study aimed to investigate the variation of molecular functional properties of peanut protein isolate (PPI) over the storage process and reveal the correlation between the PPI secondary structure and properties in the storage procedure.
Xiaotong Sun, Hua Jin, Yangyang Li, Haiying Feng, Chunhong Liu, Jing Xu   +5 more
doaj   +1 more source

Inaccurate secondary structure predictions often indicate protein fold switching

Protein Science, 2019
Although most proteins conform to the classical one‐structure/one‐function paradigm, an increasing number of proteins with dual structures and functions have been discovered.
Soumya Mishra, L. Looger, Lauren L. Porter   +2 more
semanticscholar   +1 more source

Prediction of Protein Secondary Structure

Jurnal Teknologi, 2012
Dengan wujudnya projek jujukan DNA secara besar–besaran, teknik yang tepat untuk meramalkan struktur protein diperlukan. Masalah meramalkan struktur protein daripada jujukan DNA pada dasarnya masih belum dapat diselesaikan walaupun kajian intensif telah dilakukan selama lebih daripada tiga dekad. Dalam kertas kerja ini, teori asas struktur protein
Satya N. V. Arjunan, Safaai Deris, Rosli Md. Illias   +2 more
openaire   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source