Results 21 to 30 of about 8,970,528 (379)

Proteomic screen reveals diverse protein transport between connected neurons in the visual system. [PDF]

Cell Rep, 2022
Summary: Intercellular transfer of toxic proteins between neurons is thought to contribute to neurodegenerative disease, but whether direct interneuronal protein transfer occurs in the healthy brain is not clear.
Schiapparelli LM, Sharma P, He HY, Li J, Shah SH, McClatchy DB, Ma Y, Liu HH, Goldberg JL, Yates JR, Cline HT.   +10 more
europepmc   +2 more sources

Protein Transport Protein Sec23B

Definitions, 2020
Protein transport protein Sec23B (767 aa, ~86 kDa) is encoded by the human SEC23B gene. This protein plays a role in the transport of protein from the endoplasmic reticulum to the Golgi.

semanticscholar   +1 more source

Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding

mBio, 2020
Type IV secretion systems (T4SSs) are sophisticated nanomachines used by many bacterial pathogens to translocate protein and DNA substrates across a host cell membrane.
Donghyun Park, David Chetrit, Bo Hu, Craig R. Roy, Jun Liu   +4 more
doaj   +1 more source

Bacterial Signal Peptides- Navigating the Journey of Proteins

Frontiers in Physiology, 2022
In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik, Haoze He, Ross E. Dalbey   +2 more
doaj   +1 more source

FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization

Molecular Oncology, 2020
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death.
Marta Pozniak, Aleksandra Sokolowska‐Wedzina, Kamil Jastrzebski, Jakub Szymczyk, Natalia Porebska, Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Marta Miaczynska, Jacek Otlewski, Lukasz Opalinski   +9 more
doaj   +1 more source

The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum

mBio, 2022
Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberculosis and ...
Merel P. M. Damen, Aniek S. Meijers, Esther M. Keizer, Sander R. Piersma, Connie R. Jiménez, Coenraad P. Kuijl, Wilbert Bitter, Edith N. G. Houben   +7 more
doaj   +1 more source

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

eLife, 2022
Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting ...
Holly C Ford, William J Allen, Gonçalo C Pereira, Xia Liu, Mark Simon Dillingham, Ian Collinson   +5 more
doaj   +1 more source

Protein transport in growing and steady-state cilia. [PDF]

Traffic, 2017
Lechtreck KF, Van De Weghe JC, Harris JA, Liu P.   +3 more
europepmc   +2 more sources

Mechanistic Regimes of Vibronic Transport in a Heterodimer and the Design Principle of Incoherent Vibronic Transport in Phycobiliproteins [PDF]

, 2018
Following the observation of coherent oscillations in non-linear spectra of photosynthetic pigment protein complexes, particularly phycobilliprotein such as PC645, coherent vibronic transport has been suggested as a design principle for novel light ...
Aspuru-Guzik, Alan, Bennett, Doran I. G., Kreisbeck, Christoph, Maly, Pavel, van Grondelle, Rienk   +4 more
core   +4 more sources

The Role of Light–Dark Regulation of the Chloroplast ATP Synthase

Frontiers in Plant Science, 2017
The chloroplast ATP synthase catalyzes the light-driven synthesis of ATP and is activated in the light and inactivated in the dark by redox-modulation through the thioredoxin system.
Kaori Kohzuma, John E. Froehlich, John E. Froehlich, Geoffry A. Davis, Geoffry A. Davis, Joshua A. Temple, Deepika Minhas, Amit Dhingra, Jeffrey A. Cruz, Jeffrey A. Cruz, David M. Kramer, David M. Kramer   +11 more
doaj   +1 more source