Results 21 to 30 of about 8,268,147 (364)

Bacterial Signal Peptides- Navigating the Journey of Proteins

open access: yesFrontiers in Physiology, 2022
In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik   +2 more
doaj   +1 more source

FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization

open access: yesMolecular Oncology, 2020
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death.
Marta Pozniak   +9 more
doaj   +1 more source

The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum

open access: yesmBio, 2022
Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberculosis and ...
Merel P. M. Damen   +7 more
doaj   +1 more source

TooT-T: discrimination of transport proteins from non-transport proteins [PDF]

open access: yesBMC Bioinformatics, 2020
Abstract Background Membrane transport proteins (transporters) play an essential role in every living cell by transporting hydrophilic molecules across the hydrophobic membranes. While the sequences of many membrane proteins are known, their structure and function is still not well characterized and understood, owing to the immense effort needed to ...
Munira Alballa, Gregory Butler
openaire   +4 more sources

Nucleoside Transporter Proteins

open access: yesCurrent Vascular Pharmacology, 2009
Concentrative nucleoside transporters (CNT; SLC28) and equilibrative nucleoside transporters (ENT; SLC29) mediate the uptake of natural nucleosides and a variety of nucleoside-derived drugs, mostly used in anticancer therapy. SLC28 and SLC29 families consist in three and four members, respectively, which differ in their substrate selectivity and their ...
F. Javier Casado   +2 more
openaire   +4 more sources

Thermal stability of solitons in protein $α$-helices [PDF]

open access: yesChaos, Solitons and Fractals 2022; 155: 111644, 2022
Protein$\alpha$-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The nonlinear interaction between amide I excitons and phonon deformations induced in the hydrogen-bonded lattice of peptide groups leads to self-trapping of the amide I energy, thereby creating a localized quasiparticle (soliton ...
arxiv   +1 more source

The Role of Light–Dark Regulation of the Chloroplast ATP Synthase

open access: yesFrontiers in Plant Science, 2017
The chloroplast ATP synthase catalyzes the light-driven synthesis of ATP and is activated in the light and inactivated in the dark by redox-modulation through the thioredoxin system.
Kaori Kohzuma   +11 more
doaj   +1 more source

Systemic Long-Distance Signaling and Communication Between Rootstock and Scion in Grafted Vegetables

open access: yesFrontiers in Plant Science, 2020
Grafting is widely used in fruit, vegetable, and flower propagation to improve biotic and abiotic stress resistance, yield, and quality. At present, the systemic changes caused by grafting, as well as the mechanisms and effects of long-distance signal ...
Xiaohong Lu   +5 more
doaj   +1 more source

The Dynamic SecYEG Translocon

open access: yesFrontiers in Molecular Biosciences, 2021
The spatial and temporal coordination of protein transport is an essential cornerstone of the bacterial adaptation to different environmental conditions.
Julia Oswald   +7 more
doaj   +1 more source

Inositol transport proteins [PDF]

open access: yesFEBS Letters, 2015
The cyclic polyol myo‐inositol is a key molecule in many different metabolic pathways among all organisms; in addition, it is fundamental for osmotic balance in the mammalian brain. This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in regulating the intracellular distribution and uptake of inositol.
openaire   +3 more sources

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