Natural protein proteinase inhibitors and their interaction with proteinases.
European Journal of Biochemistry, 1992 Wolfram Bode, R. Huber
semanticscholar +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase
, 1997 John Ziebuhr +2 more
openalex +2 more sources
The Prevalence and Clinical Significance of α1-Antitrypsin Deficiency (PiZ) and ANCA Specificities (Proteinase 3, BPI) in Patients with Ulcerative Colitis [PDF]
, 1999 Abdul-Nasser Elzouki +5 more
openalex +1 more source
Biased signalling and proteinase‐activated receptors (PARs): targeting inflammatory disease
British Journal of Pharmacology, 2014 M. Hollenberg +6 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Testing the influence of surfactant‐based wound dressings on proteinase activity
, 2016 Sun‐Young Jeong +2 more
openalex +2 more sources
Molecular cloning of a potential proteinase activated receptor.
Proceedings of the National Academy of Sciences of the United States of America, 1994 S. Nystedt +3 more
semanticscholar +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source