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Biochemistry of Natural Proteinase Inhibitors
Angewandte Chemie International Edition in English, 1974AbstractThe natural inhibitors of proteolytic enzymes are proteins. These inhibitors associate reversibly with the enzymes to form stoichiometric protein‐protein complexes, in which substrate‐analogous association at the active center of the enzyme results in competitive inhibition of all catalytic functions.
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Proteinase inhibitor in human tears
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1971Abstract Human tears contain an inhibitor of trypsin and chymotrypsin. Its molecular weight, between 3000 and 9000, is probably similar to that of the inhibitor from bovine organs, namely 6500. On electrophoresis at pH 8.65 the inhibitor moves toward the cathode.
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Saquinavir: An HIV Proteinase Inhibitor
1996The human immunodeficiency virus (HIV) proteinase has been recently identified as a potential target, distinct from reverse transcriptase, for antiretroviral therapy.1 Although reverse transcriptase inhibitors block viral replication in newly-infected cells by preventing this early step in the HIV replicative cycle, such antiretrovirals have no effect ...
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PROTEINASE INHIBITORS | Antichymotrypsin
2006N. Kalsheker, K. Morgan, S. Chappell
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[Proteinase inhibitors. 2. Proteinase inhibitors and insulin preparation].
Die Pharmazie, 1969I, Stokov, A, Rückert, A, Wehl
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