Results 21 to 30 of about 70,180 (311)
Molecules, 2020 Trichomoniasis, is the most prevalent non-viral sexually transmitted disease worldwide. Although metronidazole (MDZ) is the recommended treatment, several strains of the parasite are resistant to MDZ, and new treatments are required.
Natalia Mallo +3 more
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Estimation of efficacy of echinacea compositum C and teraflex application in orthodontic moving of teeth on the background of experimental goiter [PDF]
Medičnì Perspektivi, 2013 Disturbances of the thyroid status may be negatively reflected on the biological processes underlying orthodontic tooth movement. Research object – in experiment to estimate efficacy of application of drug complex with osteotropic and immunomodulating ...
Kolesnik K.A. +2 more
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Matrix metalloproteinases and their inhibitors
Фармакокинетика и Фармакодинамика, 2019 Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich +2 more
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EFFECT OF SILVER NANOPARTICLES IN EXPERIMENTAL PERITONITIS
Бюллетень сибирской медицины, 2015 In our research we have investigated the effect of intraperitoneal introduction of silver nanoparticles solution (linear particle size of 10–20 nm) into intact animals and in the simulation of experimental peritonitis.
D. V. Chegodar +2 more
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Profile of Matrix-Remodeling Proteinases in Osteoarthritis: Impact of Fibronectin
Cells, 2019 The extracellular matrix (ECM) is a complex and specialized three-dimensional macromolecular network, present in nearly all tissues, that also interacts with cell surface receptors on joint resident cells.
Selene Pérez-García +9 more
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Bacterial aspartic proteinases [PDF]
FEBS Letters, 1997 Regions of genomic DNA encoding putative aspartic proteinase domains were amplified by PCR from the bacterial species, Escherichia coli and Haemophilus influenzae. Expression of each of these DNA fragments resulted in the accumulation of the corresponding recombinant proteins in insoluble aggregates.
Hill, Jeffrey, Phylip, Lowri H
openaire +2 more sources
Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]
, 1989 Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY +7 more
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Memorias do Instituto Oswaldo Cruz, 1994 Numerous proteinase activities have been shown to be essential for the survival of Plasmodium falciparum. One approach to antimalarial chemotherapy, would be to block specifically one or several of these activities, by using compounds structurally ...
I. Florent +9 more
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Viral cysteine proteinases [PDF]
Perspectives in Drug Discovery and Design, 1996 Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded DNA viruses. The majority of these proteins are distantly related to papain or chymotrypsin and may be direct descendants of primordial proteolytic enzymes.
Gorbalenya, Alexander E. +1 more
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Pathogenetic role of proteinase-inhibitor system in the development of local and systemic pathology
Patologìâ, 2012 The experimental and clinical research of nonspecific proteinase-inhibitor system components role in pathogenesis of inflammation and ischemia-reperfusion syndrome on the level of organism and on organ level was conducted. Common mechanisms of changes
I. I. Fomochkin, A. V Kubyshkin
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