Results 31 to 40 of about 70,180 (311)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Anti-Candida Activity of Geraniol: Effect on Hydrolytic Enzyme Secretion and Biofilm Formation

Journal of Pure and Applied Microbiology, 2018
Existing antifungal drugs available today are low in efficacy, high in toxicity and cause multidrug resistance. Anti-Candida potential of geraniol, an acyclic monoterpene alcohol was evaluated and secretion of hydrolytic enzymes, adherence and biofilm ...
Yamini Sharma, Sumit Kumar Rastogi, Sahar Saadallah Amin Saadallah, Khadija Al Fadel, Nikhat Manzoor   +4 more
doaj   +1 more source

The role of proteinase enzymes in the process of conversion of muscle to meat [PDF]

Veterinarski Glasnik, 2006
Post mortem meat tenderization is a complex mechanism and unfortunately it has not been fully identified scientifically. It is known that endogenous proteinases have an important role in this mechanism.
Dümen Emek
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Bran from composite grain mixture as an object of deep processing. Part 1. Protein-proteinase complex

Пищевые системы, 2023
Deep processing of grain bran is an important, promising direction that allows the use of by-products (secondary products) of flour milling in order to obtain valuable food components for the creation of enriched food products, as well as specialized ...
I. S. Vitol, E. P. Meleshkina, G. N. Pankratov   +2 more
doaj   +1 more source

Matrix metalloproteinases-2,-3,-7,-9 and-10, but not MMP-11, are differentially expressed in normal, benign tumorigenic and malignant human keratinocyte cell lines [PDF]

, 2000
In order to investigate the correlations between constitutive proteinase expression and the degree of tumorigenicity of cancer cells we have studied a model system of three keratinocyte cell lines.
Bachmeier, B. E., Boukamp, P., Fink, E., Fusenig, N. E., Lichtinghagen, R.   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

New quality criteria for fresh frozen plasma

Медицинский вестник Юга России, 2019
Objective: development of new quality criteria for fresh frozen plasma. Matherials and methods: at diff erent times of storage of fresh frozen plasma harvested standardly and from the donors aft er Biolan exposure, the parameters of the kallikrein-kinin ...
Elena V. Ryabikina, Elena A. Chernogubova, Yuri V. Shatokhin, Irina V. Snezhko, Olga V. Gerasimova, Elvira E. Kudinova   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source