Results 31 to 40 of about 35,571 (308)

Pathogenetic role of proteinase-inhibitor system in the development of local and systemic pathology

open access: yesPatologìâ, 2012
The experimental and clinical research of nonspecific proteinase-inhibitor system components role in pathogenesis of inflammation and ischemia-reperfusion syndrome on the level of organism and on organ level was conducted. Common mechanisms of changes
I. I. Fomochkin, A. V Kubyshkin
doaj   +1 more source

Investigação sobre a adaptação do inseto praga de cereais Tenebrio molitor a inibidores de proteinases digestivas [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2010Nas larvas de Tenebrio molitor (verme do trigo) são encontrados variados tipos de proteinases ...
Alexandre, Daniel
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Anti-Candida Activity of Geraniol: Effect on Hydrolytic Enzyme Secretion and Biofilm Formation

open access: yesJournal of Pure and Applied Microbiology, 2018
Existing antifungal drugs available today are low in efficacy, high in toxicity and cause multidrug resistance. Anti-Candida potential of geraniol, an acyclic monoterpene alcohol was evaluated and secretion of hydrolytic enzymes, adherence and biofilm ...
Yamini Sharma   +4 more
doaj   +1 more source

The role of proteinase enzymes in the process of conversion of muscle to meat [PDF]

open access: yesVeterinarski Glasnik, 2006
Post mortem meat tenderization is a complex mechanism and unfortunately it has not been fully identified scientifically. It is known that endogenous proteinases have an important role in this mechanism.
Dümen Emek
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bran from composite grain mixture as an object of deep processing. Part 1. Protein-proteinase complex

open access: yesПищевые системы, 2023
Deep processing of grain bran is an important, promising direction that allows the use of by-products (secondary products) of flour milling in order to obtain valuable food components for the creation of enriched food products, as well as specialized ...
I. S. Vitol   +2 more
doaj   +1 more source

A neutron laue diffraction study of endothiapepsin: Implications for the aspartic proteinase mechanism [PDF]

open access: yes, 2001
Current proposals for the catalytic mechanism of aspartic proteinases are largely based on X-ray structures of bound oligopeptide inhibitors possessing nonhydrolyzable analogues of the scissile peptide bond.
Myles, D. A. A.   +13 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

New quality criteria for fresh frozen plasma

open access: yesМедицинский вестник Юга России, 2019
Objective: development of new quality criteria for fresh frozen plasma. Matherials and methods: at diff erent times of storage of fresh frozen plasma harvested standardly and from the donors aft er Biolan exposure, the parameters of the kallikrein-kinin ...
Elena V. Ryabikina   +5 more
doaj   +1 more source

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