Results 161 to 170 of about 111,979 (309)

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

The Chloride Channel Regulator, Calcium-Activated-1 Is Expressed in Synoviocytes and Articular Chondrocytes in Health and Disease. [PDF]

J Histochem Cytochem
Bushe J, Fürstenau J, Bartenschlager F, Dökel S, Jovanovic VM, Rösch G, Jenei-Lanzl Z, Zaucke F, Dietert K, Gruber AD.   +9 more
europepmc   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, EarlyView.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source

Correlation Between T1 Rho Value of Magnetic Resonance and Clinical Characteristics of Patients with Knee Osteoarthritis and Analysis of Related Factors of T1 Rho Value. [PDF]

Int J Gen Med
Zhao R, Xu K, Song W, Zhang T, Cao W, Pei F.   +5 more
europepmc   +1 more source

Proteoglycan-fibrillar collagen interactions.

Biochemical Journal, 1988
J. Scott
semanticscholar   +1 more source

Disruption of proteoglycan 4 (PRG4)-CD44 signaling modulates chronic synovitis in conditionally inactivated mice. [PDF]

Arthritis Res Ther
Elsaid KA, Zhang L, Zhao T, Marks A, Jenkins D, Jay GD.   +5 more
europepmc   +1 more source

Five-year histological evaluation of paclitaxel-eluting stent for an infrapopliteal lesion: a case report. [PDF]

Eur Heart J Case Rep
Hata Y, Iida O, Torii S, Shiozaki M, Mano T.   +4 more
europepmc   +1 more source

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

Journal of Clinical Investigation, 1990
S. Okuda, L. Languino, E. Ruoslahti, W. A. Border   +3 more
semanticscholar   +1 more source