Results 281 to 290 of about 130,074 (337)

Ciprofloxacin Treatment in Juvenile Mice Involves Neuronal Activation and Mimics Physical Features of Human Disease

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Tendinopathy is a complex, painful condition that affects up to 5% of the general population in their lifetime. Antibiotic treatment with fluoroquinolones has been associated with the onset of tendinopathy and tendon rupture. The mechanisms behind fluoroquinolone induced tendinopathy remain unclear. To probe activation of potentially causative
Nicole A. Chittim, Amro A. Hussien, Nicolo Dubacher, Gabor Matyas, Jess G. Snedeker   +4 more
wiley   +1 more source

Roles of TGF-β in the therapeutic potential of hypoxic mesenchymal stem cells for treating osteoarthritis in a Rabbit model. [PDF]

J Orthop Surg Res
Chiang ER, Chen KH, Ma HH, Wang JP, Ma HL.   +4 more
europepmc   +1 more source

Transcriptome analysis of granulation tissue from periodontal osseous defects

Journal of Periodontology, EarlyView.
Abstract Background Granulation tissue is routinely discarded in periodontal surgical procedures, but few studies have characterized it. The present study aimed to compare global gene expression in granulation tissue derived from different types of periodontal osseous defects.
Ye Han Sam, Ana J. Caetano, Dewi R. Owen, Giuseppe Mainas, Luigi Nibali, Mandeep Ghuman   +5 more
wiley   +1 more source

Effect of Long-Term Smoking on Cervical Disc Degeneration: A Retrospective Study. [PDF]

Med Sci Monit
Kiraz M, Kina H.
europepmc   +1 more source

GLIS2 Promotes Epithelial‐Mesenchymal Transition and Gastric Cancer Progression by Regulating BGN to Activate the Wnt/β‐Catenin Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study elucidates the mechanism by which GLIS Family Zinc Finger 2 (GLIS2) promotes epithelial‐mesenchymal transition (EMT) in gastric cancer through biglycan (BGN) activation and Wnt/β‐catenin stimulation. By analyzing 18 pairs of GC tissues and establishing in vitro models (combining GLIS2 knockdown/BGN overexpression with Wnt pathway ...
Juan Yan, Ya‐Peng Deng
wiley   +1 more source

Functional Benefits of Low-Molecular-Weight Collagen Peptide in Achilles Tendon and Medial Collateral Ligament Injuries and Anterior Cruciate Ligament Transection-Induced Osteoarthritis. [PDF]

J Microbiol Biotechnol
Choi E, Kim M, Lee DH, Shim S, Kim DU, Hong JM, Chung HC.   +6 more
europepmc   +1 more source

Therapeutic Window of Laser Dosimetry for the Treatment of Knee Osteoarthritis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives We propose a non‐destructive laser method that uses controlled thermomechanical action to treat degenerative cartilage changes. The technique aims to reduce pain, offers a minimally invasive option for early‐ to mid‐stage degeneration, and lessens the need for joint replacement.
Yulia Alexandrovskaya, Felix Feldchtein, Andreas Glatz, Anatoly Shekhter, Elizaveta Kon, Valerii Vinokur, Emil Sobol   +6 more
wiley   +1 more source

Mechanical signalling in osteoarticular tissues [PDF]

, 2010
Lee, Herng-Sheng, Salter, Donald
core  

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

Macromolecular Materials and Engineering, EarlyView.
This study develops a biomimetic bilayer scaffold based on gelatin methacryloyl‐ciprofloxacin/polycaprolactone‐collagen (GelMA‐CIP/PCL‐COL), designed to release EGF and TGFβ3 in a controlled manner. The GelMA‐CIP@PVA‐EGF/PCL‐COL@PVA‐TGFβ3 scaffold currently demonstrates sustained delivery of growth factors for 28 days, mechanical properties similar to ...
Hilal Yilmaz, Sevda Gursoy, Gulsah Torkay, Shhd Saraj, Louna Karzoun, Alpay Kose, Mert Akin Insel, Ridvan Yildirim, Ayca Bal Ozturk, Ayse Ceren Calikoglu Koyuncu, Oguzhan Gunduz, Cem Bulent Ustundag   +11 more
wiley   +1 more source