Results 41 to 50 of about 3,884 (232)

Divergent responses of the diatom Thalassiosira weissflogii to ocean acidification during light and dark periods

Limnology and Oceanography Letters, Volume 11, Issue 3, May 2026.
Abstract Given the limited understanding of discrepancies in responses of diatoms to ocean acidification (OA), we comparatively investigated the physiological and transcriptional performances of a diatom Thalassiosira weissflogii acclimated to OA (pHt drop of 0.35–0.41) between day and night periods.
Guang Gao, Liming Qu, Jingke Ge, Kunshan Gao   +3 more
wiley   +1 more source

Comparison of Outer Membrane Vesicles of Three Different Isolates from Pseudomonas aeruginosa

Vaccine Research, 2019
Introduction: Pseudomonas aeruginosa (PA) is an opportunistic mucosal human pathogen responsible for a wide range of acute and chronic infections. PA releases outer membrane vesicles (OMVs) in all situations and environments.
Fereshteh Satarian, Taher Nejadsattari, Farzam Vaziri, Seyed Davar Siadat   +3 more
doaj  

Luminal acidification of diverse organelles by V-ATPase in animal cells [PDF]

, 2000
Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5.
Futai, Masamitsu, Kanazawa, Hiroshi, Moriyama, Yoshinori, Oka, Toshihiko, Sun-Wada, Ge-hong, Wada, Yoh   +5 more
core  

APOE4 Drives Sex‐ and Diet‐Dependent Effects on AD‐Like Pathology, Cognition, and Mitochondrial Function

FASEB BioAdvances, Volume 8, Issue 5, May 2026.
APOE4 interacts with sex and diet to influence brain mitochondrial function. ABSTRACT Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD), yet it's unclear how this allele promotes disease. While factors like diet and sex may modify AD susceptibility in APOE4 carriers, the interaction between these factors is ...
Chelsea N. Johnson, Colton R. Lysaker, Xin Cao, Vivien Csikos, Frederick Boakye, Paul J. Kueck, Edziu Franczak, Paige C. Geiger, Jill K. Morris, John P. Thyfault, Heather M. Wilkins   +10 more
wiley   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females?

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn, Nuria Alvarez‐Sanchez, Lawrence Steinman   +2 more
wiley   +1 more source

CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile Toxins

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Enteric glia in humans, mice, and rats express all known receptors for TcdA (LDLR) and TcdB (CSPG4, FZD‐1, FZD2, FZD7, PVRL3, TFPI, LRP1). CSPG4 expression is increased in colonic tissues from humans and mice with C. difficile infection, as well as in rat enteric glia exposed to TcdA or TcdB. C.
Francisco M. S. Marques, Deiziane V. S. Costa, Conceição S. M. Rebouças, Gerly A. C. Brito, Cirle A. Warren, Renata F. C. Leitão   +5 more
wiley   +1 more source

Genomic Reconstruction of an Uncultured Hydrothermal Vent Gammaproteobacterial Methanotroph (Family Methylothermaceae) Indicates Multiple Adaptations to Oxygen Limitation [PDF]

, 2015
Hydrothermal vents are an important contributor to marine biogeochemistry, producing large volumes of reduced fluids, gasses, and metals and housing unique, productive microbial and animal communities fueled by chemosynthesis.
Chan, Ken Y., Gradinaru, Viviana, Metcalfe, Kyle, Michel, Alice, Mullin, Sean, Orphan, Victoria J., Skennerton, Connor T., Valiente, Chanel, Ward, Lewis M.   +8 more
core   +2 more sources

Human Peripheral Myelin Protein 2 and Charcot–Marie–Tooth Disease or Structural Missense Variants Show Different Binding to Myelin‐Like Lipid Monolayers

ChemBioChem, Volume 27, Issue 8, April 2026.
We compare the membrane affinity of the P2 myelin protein and its Charcot–Marie–Tooth disease variants on a myelin‐like lipid monolayer. Epifluorescence microscopy reveals different two‐dimensional (2D) clustering and pressure‐dependent binding. Single‐point mutations in the P2 β‐barrel and α‐helix affect affinity.
Florian Arndt Schöffmann, Md Abdus Shukur Imran, Christian Schwieger, Øystein Hetland, Vanessa Jerschabek, Arne Raasakka, Petri Kursula, Dariush Hinderberger   +7 more
wiley   +1 more source

Identification And Characterization Of A Second Encephalitogenic Determinant Of Myelin Proteolipid Protein (Residues 178-191) For SJL Mice [PDF]

, 1992
We previously described a synthetic peptide of myelin proteolipid protein (PLP), peptide 139-151, which induces experimental allergic encephalomyelitis in SJL/J (H-2s) mice.
Greer, J. M., Kuchroo, V. K., Lees, M. B., Sobel, R. A.   +3 more
core  

Brain Proteolipids [PDF]

European Journal of Biochemistry, 1983
Proteolipid apoproteins have been isolated from a whole bovine brain homogenate by chloroform/methanol extraction, and fractionated by chromatography on modified (lipophilic) Sephadex, followed by ion‐exchange chromatography on CM‐Trisacryl. The various final, highly hydrophobic, fractions are homogeneous (sodium dodecyl sulfate/polyacrylamide gel ...
G, Helynck, B, Luu, J L, Nussbaum, D, Picken, G, Skalidis, E, Trifilieff, A, Van Dorsselaer, P, Seta, R, Sandeaux, C, Gavach, F, Heitz, D, Simon, G, Spach   +12 more
openaire   +2 more sources