Results 51 to 60 of about 3,884 (232)
Real‐time feedback strategically regulates optoelectronics for customized optogenetic spinal cord regeneration. ABSTRACT Previous optogenetic bioelectronic systems have enabled a highly selective way of modulating neural populations by delivering a certain wavelength of light to engage with exogenously expressed light‐sensitive proteins, which lay the ...
Kaishun Xia +17 more
wiley +1 more source
Chromosomal assignment of genes controlling salt-soluble proteins (albumins and globulins) in wheat and related species [PDF]
alt-soluble proteins from the endosperms of wheat, barley, and rye have been separated by nonequilibrium electrofocusing x electrophoresis. Genes encoding 14 of the 25 components observed in wheat have been unambiguously assigned to 10 different ...
Aragoncillo Ballesteros, Cipriano +3 more
core +2 more sources
The uncinate fasciculus (UF), which serves to connect the anterior temporal lobe and the orbitofrontal cortex, is a highly understudied white matter fiber bundle. In this study, we characterized the fatty acid (FA) profile of myelin phospholipids in a fraction‐specific manner, as well as the cholesterol concentrations, in the human postmortem UF.
Kelly Perlman +6 more
wiley +1 more source
Altered expression of neuroplasticity-related genes in the brain of depressed suicides [PDF]
Background: Expression of the neuronal membrane glycoprotein M6a (GPM6A), the proteolipid protein (PLP/DM20) family member, is downregulated in the hippocampus of chronically stressed animals.
Alvarez Juliá, Anabel +4 more
core +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Carbon-dependent control of electron transfer and central carbon pathway genes for methane biosynthesis in the Archaean, Methanosarcina acetivorans strain C2A [PDF]
BackgroundThe archaeon, Methanosarcina acetivorans strain C2A forms methane, a potent greenhouse gas, from a variety of one-carbon substrates and acetate.
Lars Rohlin, Robert P Gunsalus
core +2 more sources
Endogenous Repair in Vanishing White Matter
[Color figure can be viewed at www.annalsofneurology.org] Objective Vanishing white matter is a leukodystrophy with remarkable regional variation in disease severity. The cerebral and cerebellar white matter chronically degenerates, while stress‐induced episodes of rapid neurological deterioration coincide with the appearance of acute focal lesions in ...
Bonnie C. Plug +7 more
wiley +1 more source
Gemcitabine-mediated tumour regression and p53-dependent gene expression: implications for colon and pancreatic cancer therapy [PDF]
Gemcitabine is a chemotherapeutic that is widely used for the treatment of a variety of haematological malignancies and has become the standard chemotherapy for the treatment of advanced pancreatic cancer. Combinational gemcitabine regimes (e.g.
A Suzuki +43 more
core +1 more source
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity
CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert +14 more
wiley +1 more source

