Results 71 to 80 of about 31,301 (210)

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

open access: yesAdvanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang   +10 more
wiley   +1 more source

Sarcomere length influences proteolysis

open access: yes, 2007
The overall objective of this research was to determine the role of sarcomere length on postmortem proteolysis as it relates to beef tenderness. The first two studies established that sarcomere length influences postmortem proteolysis of troponin T (TnT)
Weaver, Amanda D
core  

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

open access: yesAdvanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee   +3 more
wiley   +1 more source

Solid‐State Nanopore Characterization of Dendrimer‐Peptide Conjugates Across Defined Peptide Loadings

open access: yesAdvanced Materials Interfaces, EarlyView.
Solid‐state nanopores are used to interrogate dendrimer‐peptide conjugates with systematically varied peptide loading. Single‐particle ionic current signatures reveal how ligand density modulates deformability, transport pathways, and electromechanical coupling during translocation.
Chaoming Gu   +7 more
wiley   +1 more source

Peptidomics for Studying Limited Proteolysis

open access: yes, 2015
Limited proteolysis is a pivotal mechanism regulating protein functions. Identifying physiologically or pathophysiologically relevant cleavage sites helps to develop molecular tools that can be used for diagnostics or therapeutics.
Kazuki Sasaki (800935)   +3 more
core   +2 more sources

Is enhanced free radical flux associated with increased intracellular proteolysis?

open access: yes, 1987
Intracellular proteolysis was measured in cultured cells during and after radical attack. Radicals were generated firstly, throughout the aqueous phase by gamma irradiation and secondly, selectively, either extracellularly or intracellularly by chemical ...
Gillian S. Vince   +3 more
core   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

open access: yesAdvanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang   +4 more
wiley   +1 more source

Probing Protein Structure by Limited Proteolysis [PDF]

open access: yes, 2004
Limited proteolysis experiments can be successfully used to probe conformational features of proteins. In a number of studies it has been demonstrated that the sites of limited proteolysis along the polypeptide chain of a protein are characterized by ...
PICOTTI P.   +8 more
core  

Inhibition of fibrin polymerization by fibrinogen proteolysis products

open access: yes, 1962
The action of fibrinogen proteolysis products in inhibiting fibrinogen-fibrin conversion by thrombin has excited considerable interest because of its possible significance in blood coagulation.
Norma Alkjaersig   +3 more
core   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

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