Results 1 to 10 of about 205,030 (174)
Quality Control—A Stepchild in Quantitative Proteomics: A Case Study for the Human CSF Proteome
Biomolecules, 2023 Proteomic studies using mass spectrometry (MS)-based quantification are a main approach to the discovery of new biomarkers. However, a number of analytical conditions in front and during MS data acquisition can affect the accuracy of the obtained outcome.
Svitlana Rozanova +7 more
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Intact Transition Epitope Mapping—Serological Inspection by Epitope EXtraction (ITEM—SIX)
Molecules, 2023 Precision medicine requests accurate serological inspections to precisely stratify patients for targeted treatment. Intact transition epitope mapping analysis proved surrogate seroconversion of a model organism’s serum when spiked with a monoclonal ...
Agatino Zammataro +4 more
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Molecules, 2020 Electrospray mass spectrometry is applied to determine apparent binding energies and quasi equilibrium dissociation constants of immune complex dissociation reactions in the gas phase. Myoglobin, a natural protein-ligand complex, has been used to develop
Bright D. Danquah +4 more
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BMC Bioinformatics, 2023 Background The analysis of mass spectrometry-based quantitative proteomics data can be challenging given the variety of established analysis platforms, the differences in reporting formats, and a general lack of approachable standardized post-processing ...
Jeff Jones +5 more
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Frontiers in Chemistry, 2021 N-Glycosylation is one of the most common and important post-translational modification methods, and it plays a vital role in controlling many biological processes.
Zhiya Fan +5 more
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Characterization of the E.coli proteome and its modifications during growth and ethanol stress
Frontiers in Microbiology, 2015 We set out to provide a resource to the microbiology community especially with respect to systems biology based endeavors. To this end, we generated a comprehensive dataset monitoring the changes in protein expression, copy number, and post translational
Boumediene eSoufi +3 more
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Microorganisms, 2022 Currently, the world is struggling with the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
George Tetz, Victor Tetz
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Military Medical Research, 2023 The rapid development of genome editing technology has brought major breakthroughs in the fields of life science and medicine. In recent years, the clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing toolbox has been ...
Zhen-Hua Li +4 more
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Sampling the proteome by emerging single-molecule and mass-spectrometry methods [PDF]
Nat Methods 20, 339--346 (2023), 2022 Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine these implications for both liquid chromatography-tandem mass spectrometry (LC-MS/MS) and single-molecule counting ...
arxiv +1 more source
BMC Genomics, 2017 Background RNA sequencing (RNA-seq) and microarrays are two transcriptomics techniques aimed at the quantification of transcribed genes and their isoforms.
Petr V. Nazarov +8 more
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