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A model of large-scale proteome evolution [PDF]

Advances in Complex Systems 5, 43 (2002), 2002
The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have shown that its
Kepler, Thomas B., Pastor-Satorras, Romualdo, Smith, Eric, Sole, Ricard V.   +3 more
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Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy [PDF]

, 2010
Background: Urine proteome analysis is rapidly emerging as a tool for diagnosis and prognosis in disease states. For diagnosis of diabetic nephropathy (DN), urinary proteome analysis was successfully applied in a pilot study.
A Kottgen, Alaa Alkhalaf, AS Levey, BA Julian, BA Julian, Bart Janssen, Beate Tiran, BJ Williams, Brigitte M. Winklhofer-Roob, CD Stehouwer, Christine Fischer, D Fliser, D McLerran, D Theodorescu, DM Good, DM Good, DM Good, DM Good, EM Weissinger, F Goodsaid, F Huang, Gerjan J. Navis, H Mischak, Harald Mischak, Harald Sourij, Henk J. G. Bilo, HH Parving, Ivan Rychlík, J Jantos-Siwy, JK Snell-Bergeon, JM DeLeo, Johannes M. Roob, K Rossing, K Rossing, K Rossing, KA Baggerly, Karel Medek, Kasper Rossing, M Girolami, M Haubitz, MA Knepper, Marie Cerna, Massimo Federici, N Neuhoff, O Soylemezoglu, P Lescuyer, P Zürbig, P Zürbig, Peter Rossing, Petra Zürbig, PV Rao, S Decramer, S Schaub, S Wittke, SA Varghese, Sebastian Fuchs, Stephan J. L. Bakker, TY Wong, Y Benjamini, YM Smulders, ZR Yang, ZR Yang   +61 more
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Proteomics

Journal of Education, Health and Sport, 2021
Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions. Proteomics is studied by proteins that are expressed in a given cell, tissue or organism over a period of time (under certain conditions). It is
Dolomatov, S.I., Kazakova, V.V., Zukow, W.   +2 more
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Proteomics of Brucella [PDF]

Proteomes, 2020
Brucella spp. are Gram negative intracellular bacteria responsible for brucellosis, a worldwide distributed zoonosis. A prominent aspect of the Brucella life cycle is its ability to invade, survive and multiply within host cells. Comprehensive approaches, such as proteomics, have aided in unravelling the molecular mechanisms underlying Brucella ...
Ansgar Poetsch, Ansgar Poetsch, María Inés Marchesini   +2 more
openaire   +6 more sources

Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models. [PDF]

, 2018
Knowing the catalytic turnover numbers of enzymes is essential for understanding the growth rate, proteome composition, and physiology of organisms, but experimental data on enzyme turnover numbers is sparse and noisy.
Desouki, Abdelmoneim Amer, Ha, Yuanchi, Haiman, Zachary B, Haiman, Zachary B, Heckmann, David, Lercher, Martin J, Lloyd, Colton J, Mih, Nathan, Palsson, Bernhard O, Zielinski, Daniel C   +9 more
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Subcellular proteomics [PDF]

Nature Reviews Methods Primers, 2021
The eukaryotic cell is compartmentalized into subcellular niches, including membrane-bound and membrane-less organelles. Proteins localize to these niches to fulfil their function, enabling discreet biological processes to occur in synchrony. Dynamic movement of proteins between niches is essential for cellular processes such as signalling, growth ...
Josie A. Christopher, Charlotte Stadler, Claire E. Martin, Marcel Morgenstern, Yanbo Pan, Cora N. Betsinger, David G. Rattray, Diana Mahdessian, Anne-Claude Gingras, Bettina Warscheid, Janne Lehtiö, Ileana M. Cristea, Leonard J. Foster, Andrew Emili, Kathryn S. Lilley   +14 more
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Weight matrix based identification of terpene synthases conserved motifs in Arabidopsis thaliana proteome [PDF]

, 2012
Terpenes comprise the most diverse collection of natural products. Out of more than 30,000 individual terpenoids identified, at least half are synthesized by plants. A relatively small, but quantitatively significant, number of terpenoids are involved in
Feroz Khan, Suaib Luqman, Suchita Srivastava   +2 more
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Proteomic Approach for Extracting Cytoplasmic Proteins from Streptococcus sanguinis using Mass Spectrometry [PDF]

, 2017
Streptococcus sanguinis is a commensal and early colonizer of oral cavity as well as an opportunistic pathogen of infectious endocarditis. Extracting the soluble proteome of this bacterium provides deep insights about the physiological dynamic changes ...
Elrami, Fadi, Nelson, Kristina, Xu, Ping
core   +3 more sources

Proteomes: A New Proteomic Journal [PDF]

Proteomes, 2012
In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis.
openaire   +4 more sources

Positional proteomics reveals differences in N-terminal proteoform stability [PDF]

, 2016
To understand the impact of alternative translation initiation on a proteome, we performed a proteome-wide study on protein turnover using positional proteomics and ribosome profiling to distinguish between N-terminal proteoforms of individual genes.
Brown JL, Daria Gawron, Elvis Ndah, Kris Gevaert, Petra Van Damme   +4 more
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