Results 111 to 120 of about 538,471 (385)
Systems biology of energetic and atomic costs in the yeast transcriptome, proteome, and metabolome [PDF]
, 2008 Proteins vary in their cost to the cell and natural selection may favour the use of proteins that are cheaper to produce. We develop a novel approach to estimate the amino acid biosynthetic cost based on genome-scale metabolic models, and directly ...
Balazs Papp +5 more
core +2 more sources
Nature Communications, 2019 We describe pLink 2, a search engine with higher speed and reliability for proteome-scale identification of cross-linked peptides. With a two-stage open search strategy facilitated by fragment indexing, pLink 2 is ~40 times faster than pLink 1 and 3~10 ...
Zhenlin Chen +15 more
semanticscholar +1 more source
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona
Nature Communications, 2020 Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma proteome. Here we report a highly parallel protein quantitation platform integrating nanoparticle (NP) protein coronas with liquid chromatography-mass spectrometry ...
J. Blume +24 more
semanticscholar +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Proteomic analysis of DEN and CCl4-induced hepatocellular carcinoma mouse model
Scientific ReportsHepatocellular carcinoma (HCC) seriously threatens human health, mostly developed from liver fibrosis or cirrhosis. Since diethylnitrosamine (DEN) and carbon tetrachloride (CCl4)-induced HCC mouse model almost recapitulates the characteristic of HCC with
Qian Zhang +8 more
doaj +1 more source
Molecular & Cellular Proteomics, 2002 The human plasma proteome holds the promise of a revolution in disease diagnosis and therapeutic monitoring provided that major challenges in proteomics and related disciplines can be addressed.
N. Anderson, N. Anderson
semanticscholar +1 more source
Programmed ‘disarming’ of the neutrophil proteome reduces the magnitude of inflammation
Nature Immunology, 2020 The antimicrobial functions of neutrophils are facilitated by a defensive armamentarium of proteins stored in granules, and by the formation of neutrophil extracellular traps (NETs).
J. M. Adrover +16 more
semanticscholar +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Evaluation of four different strategies to characterize plasma membrane proteins from banana roots [PDF]
, 2015 Plasma membrane proteins constitute a very important class of proteins. They are involved in the transmission of external signals to the interior of the cell and selective transport of water, nutrients and ions across the plasma membrane.
Carpentier, Sebastien C. +3 more
core +1 more source