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Proteome Discoverer—A Community Enhanced Data Processing Suite for Protein Informatics
Proteomes, 2021 Proteomics researchers today face an interesting challenge: how to choose among the dozens of data processing and analysis pipelines available for converting tandem mass spectrometry files to protein identifications.
Benjamin C. Orsburn
semanticscholar +1 more source
RIBAR and xRIBAR: methods for reproducible relative MS/MS-based label-free protein quantification [PDF]
, 2011 Mass spectrometry-driven proteomics is increasingly relying on quantitative analyses for biological discoveries. As a result, different methods and algorithms have been developed to perform relative or absolute quantification based on mass spectrometry ...
Colaert, Niklaas +2 more
core +1 more source
Proteomic Analysis to Identify Tightly-Bound Cell Wall Protein in Rice Calli. [PDF]
, 2015 Rice is a model plant widely used for basic and applied research programs. Plant cell wall proteins play key roles in a broad range of biological processes. However, presently, knowledge on the rice cell wall proteome is rudimentary in nature.
Chen, Xiong Yan +10 more
core +1 more source
OsteoporosAtlas: a human osteoporosis-related gene database [PDF]
PeerJ, 2019 Background Osteoporosis is a common, complex disease of bone with a strong heritable component, characterized by low bone mineral density, microarchitectural deterioration of bone tissue and an increased risk of fracture.
Xun Wang +13 more
doaj +2 more sources
Proteoforms expand the world of microproteins and short open reading frame-encoded peptides
iScience, 2023 Summary: Microproteins and short open reading frame-encoded peptides (SEPs) can, like all proteins, carry numerous posttranslational modifications. Together with posttranscriptional processes, this leads to a high number of possible distinct protein ...
Liam Cassidy +2 more
doaj +1 more source
Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]
, 2020 With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria +3 more
core +2 more sources
Toward an understanding of the protein interaction network of the human liver
Molecular Systems Biology, 2011 Proteome‐scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery.
Jian Wang +37 more
doaj +1 more source
Multidimensional separation prior to mass spectrometry: Getting closer to the bottom of the iceberg [PDF]
, 2013 While prefractionation has previously been shown to improve results in MS analysis, a novel combination provides an additional dimension of separation: protein fractionation by SDS-PAGE followed by IEF of tryptic peptides before separation by RP-LC ...
Mayr, Manuel, Rabilloud, Thierry
core +4 more sources
Journal of Thrombosis and Haemostasis, 2003 As anucleate cell particles, platelets do not lend themselves to analysis by traditional cell and molecular biology techniques. Moreover, while valuable information may be gleaned from studies of messenger RNA in platelets, the rapid events in platelets are not governed by or dependent on alterations in gene expression.
P B, Maguire, D J, Fitzgerald
openaire +2 more sources
Nature Communications, 2019 Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear.
Wenting Yang +10 more
doaj +1 more source