Results 61 to 70 of about 505,018 (335)
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis
Nature Communications, 2018 Microtubule asters originate from centrosomes but their role during interphase remains largely unknown. Here, the authors find that microtubule asters anchored by previously-uncharacterized FSD1 play a role in ciliogenesis by maintaining the dynamic ...
Hai-Qing Tu +16 more
doaj +1 more source
How can we use proteomics to learn more about platelets?
Platelets, 2023 Proteomics tools provide a powerful means to identify, detect, and quantify protein-related details in studies of platelet phenotype and function.
Joseph E. Aslan
doaj +1 more source
Nanotechnologies in Proteomics [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Victor A. Bykov +3 more
openaire +4 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Scientific Reports, 2017 Sialylation is a glycosylation feature that occurs in different linkages at the non-reducing end of a glycan moiety, the linkage isomers are often differentially associated with various biological processes.
Guinevere S. M. Kammeijer +7 more
doaj +1 more source
Identifying individuals using proteomics: are we there yet?
Frontiers in Molecular Biosciences, 2022 Multi-omics approaches including proteomics analyses are becoming an integral component of precision medicine. As clinical proteomics studies gain momentum and their sensitivity increases, research on identifying individuals based on their proteomics ...
Ivo Fierro-Monti +3 more
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Frontiers in Immunology, 2021 Recently, a mass spectrometry-based approach was introduced to directly assess the IgG1 immunoglobulin clonal repertoires in plasma. Here we expanded upon this approach by describing a mass spectrometry-based technique to assess specifically the clonal ...
Albert Bondt +9 more
doaj +1 more source
MSFragger: ultrafast and comprehensive peptide identification in shotgun proteomics
Nature Methods, 2017 There is a need to better understand and handle the 'dark matter' of proteomics—the vast diversity of post-translational and chemical modifications that are unaccounted in a typical mass spectrometry–based analysis and thus remain unidentified.
Andy T. Kong +4 more
semanticscholar +1 more source
Proteomics of the Spermatozoon [PDF]
Balkan Journal of Medical Genetics, 2012 ABSTRACT The study of the sperm proteins is crucial for understanding its normal function and alterations in infertile patients. The sperm is a highly specialized cell with a very large flagella, with little cytoplasm and a highly condensed nucleus. The most abundant proteins in the nucleus of mammalian sperm are the protamines. The main functions
JL Ballescá, R Oliva
openaire +4 more sources