Results 91 to 100 of about 719 (174)
Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.Abstract BACKGROUND Retinal microvascular alterations, detectable via color fundus photography (CFP), may reflect cerebral microvascular pathology in Alzheimer's disease (AD). However, their associations with blood‐based biomarkers and cerebral small vessel disease (SVD) remain unclear.
William Robert Kwapong +16 more
wiley +1 more source
Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.Abstract INTRODUCTION Assessing brain health and identifying cognitive impairment risk remains challenging, with only 11.4% of MCI cases receiving timely diagnoses. We developed the Brain Health Index (BHI), integrating the Vulnerability Index, Resilience Index, and Number Symbol Coding Task into a unified metric. METHODS We evaluated 469 participants (
Michael J. Kleiman +3 more
wiley +1 more source
Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.Abstract INTRODUCTION The relationships between blood homocysteine (Hcy), amyloid beta (Aβ), tau pathology, and their combined effects on cortical thinning and cognitive impairment in Alzheimer's disease (AD) remain poorly understood. METHODS Participants were stratified into Aβ+ and Aβ− groups by positron emission tomography.
Qiang Wang +32 more
wiley +1 more source
Cytometry Part A, Volume 107, Issue 6, Page 390-403, June 2025.ABSTRACT Suspension and imaging mass cytometry are single‐cell, proteomic‐based methods used to characterize tissue composition and structure. Data assessing the consistency of these methods over an extended period of time are still sparse and are needed if mass cytometry‐based methods are to be used clinically.
Ruben Casanova +141 more
wiley +1 more source
Chemical Proteomics Reveals Human Off‐Targets of Fluoroquinolone Induced Mitochondrial Toxicity
Angewandte Chemie International Edition, Volume 64, Issue 18, April 25, 2025.A schematic overview of the adverse effects of Ciprofloxacin related to mitochondrial toxicity. AIFM1 plays a role in the MIA40‐mediated import into the IMS and oxidative folding of nuclear‐encoded proteins, including ETC complexes I and IV subunits. Ciprofloxacin disrupts the IMS import machinery, impairing ETC function.
Till Reinhardt +14 more
wiley +1 more source
Adenoviromics: Mining the Human Adenovirus Species D Genome [PDF]
, 2018 Human adenovirus (HAdV) infections cause disease world-wide. Whole genome sequencing has now distinguished 90 distinct genotypes in 7 species (A-G).
Ashrafali M. Ismail +9 more
core +1 more source
An Investigation of High-throughput Proteomic Analysis in Marine Dinoflagellate (Symbiodiniaceae) [PDF]
, 2021 University of Technology Sydney. Faculty of Science.The marine dinoflagellate in the family Symbiodiniaceae has received increasing attention due to its symbiotic interaction with reef-building corals.
Supasri, Kanoknate May
core
Bleeding disorder of unknown cause:an illustrated review on current practice, knowledge gaps, and future perspectives [PDF]
In more than half of the individuals with a clinically relevant bleeding tendency who are referred to hemostasis experts, no biological etiology can be found after extensive laboratory testing.
+17 more
core +3 more sources
Iron metabolism and biomarkers in idiopathic pulmonary arterial hypertension
, 2011 Idiopathic pulmonary arterial hypertension (IPAH) is a progressive disease characterised by increased vascular resistance and remodelling of the pulmonary vasculature.
Rhodes, Christopher James +1 more
core +1 more source
In taberna quando sumus: A Drunkard’s Cakewalk Through Wine Proteomics
Food Technology and Biotechnology, 2012 Analysis of white and red wine trace proteomes via capture with combinatorial peptide ligand libraries (CPLL) is reported here. Most of the alcoholic beverages tested (all of Italian origin) were found to contain only traces of casein (on average from 20
Pier Giorgio Righetti +3 more
doaj