Results 111 to 120 of about 190,185 (400)
Medicina, 2019 Background and Objective: Evidence indicates that genetic factors may be involved in the risk of ischemic stroke (IS). The aim of this study was to assess the effect of genetic polymorphisms located in exons or untranslated regions of MTHFR as well as FV
Seyed Mehdi Hashemi +7 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
, 1994 The cDNA sequences of chicken and hagfish prothrombin have been determined. The sequences predict that prothrombin from both species is synthesized as a prepro-protein consisting of a putative Gla domain, two kringle domains, and a two-chain protease ...
Banfield, David K. +3 more
core +1 more source
Canadian Medical Association Journal, 2013 Background: ABO blood type locus has been reported to be an important genetic determinant of venous and arterial thrombosis in genome-wide association studies. We tested the hypothesis that ABO blood type alone and in combination with mutations in factor
B. F. Sode +4 more
semanticscholar +1 more source
USE in prothrombin 3′-UTR influences the selection of the natural prothrombin cleavage site
, 2011 Copyright information:Taken from "The relationship between the prothrombin upstream sequence element and the G20210A polymorphism: the influence of a competitive environment for mRNA 3′-end formation"Nucleic Acids Research 2005;33(3):1010-1020.Published ...
Jeffrey Wilusz (6673) +3 more
core +1 more source
Factor V Leiden, prothrombin, MTHFR, and PAI-1 gene polymorphisms in patients with arterial disease: A comprehensive systematic-review and meta-analysis [PDF]
, 2023 Emanuele Valeriani +5 more
openalex +1 more source
BMC Surgery, 2013 BackgroundIn patients with cirrhosis, the synthesis of coagulation factors can fall short, reflected by a prolonged prothrombin time. Although anticoagulants factors are decreased as well, blood loss during orthotopic liver transplantation can still be ...
Freeha Arshad +14 more
semanticscholar +1 more source
Prothrombin G20210A is a bifunctional gene polymorphism
, 2002 The G20210A polymorphism has been shown to alter the efficiency of prothrombin mRNA processing. Here we show that the G20210A mutation also alters prothrombin mRNA stability.
Mythily Sachchithananthan +9 more
core +1 more source
Frequency of Factor V Leiden and Prothrombin Polymorphism in South of Iran [PDF]
Iranian Journal of Medical Sciences, 2009 Normal hemostasis requires balanced regulation of prothromboticand antithrombotic factors. Inherited alteration of factor Vand prothrombin gene, the G20210A mutation, increases the resistanceof factor V to degradation and booster production ofprothrombin
Javad Dehbozorgian +6 more
doaj
, 2005 The prothrombin G20210A mutation has been described as the second most common genetic risk factor in thrombotic patients. Recently a new prothrombin gene variant namely prothrombin C20209T has also been found to be associated with thrombosis.
Gurgey, A +4 more
core +1 more source