Results 101 to 110 of about 134,214 (298)

Elevated Prothrombin Promotes Venous, but Not Arterial, Thrombosis in Mice [PDF]

, 2013
Individuals with elevated prothrombin, including those with the prothrombin G20210A mutation, have increased risk of venous thrombosis. Although these individuals do not have increased circulating prothrombotic biomarkers, their plasma demonstrates ...
Heisler, M. J., Byrnes, J. R., Machlus, K. R., Cooley, B. C., Aleman, M. M., Walton, B. L., Wang, J.-G., Wolberg, A. S.   +7 more
core   +1 more source

Using Labs Wisely: A collaboration between Choosing Wisely Canada and over 150 Canadian hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Many in‐hospital laboratory tests are unnecessary. Unnecessary testing is associated with patient harm, fiscal inefficiency, and environmental waste. Objectives In 2021, Choosing Wisely Canada launched the Using Labs Wisely (ULW) hospital collaborative to (1) build national expertise on reducing unnecessary testing, (2) share ...
Thomas Bodley, Bilal Shakir, Gillian Hurwitz, Adina Weinerman, Lisha Lo, Saranya Arnoldo, Chloe Chow, Janet Simons, Wendy Levinson   +8 more
wiley   +1 more source

A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

Clinical Case Reports
Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant.
Cecilia Augustsson, Knut Taxbro, Karin Strandberg, Eva Zetterberg   +3 more
doaj   +1 more source

Prothrombin Activity and Concentration in Healthy Subjects with and without the Prothrombin G20210A Mutation

, 2000
A common mutation in the prothrombin gene (G20210A) is associated with elevated prothrombin levels and thrombosis. The pathomechanism related to the G20210A mutation is currently not understood and the interdependence of prothrombin activity and ...
Ehrenreich, Hannelore, Piotr Lewczuk, Oellerich, Michael, Ekkehard Schütz, Nicolas von Ahsen, Michael Oellerich, Schütz, Ekkehard, Hannelore Ehrenreich, von Ahsen, Nicolas, Lewczuk, Piotr   +9 more
core   +1 more source

Early prediction of acute kidney injury in traumatic and non‐traumatic rhabdomyolysis using an interpretable machine learning model: A multicenter study with external validation

Journal of Intelligent Medicine, EarlyView.
Abstract Acute kidney injury (AKI) is a common and severe complication of rhabdomyolysis (RM), and early risk stratification remains challenging because of its multifactorial and heterogeneous nature. We developed and externally validated an interpretable machine learning (ML) model for early prediction of AKI in RM across traumatic and non‐traumatic ...
Chunli Liu, Jie Shi, Fengjuan Wang, Liang Ma, Huangang Hu, Li Zhang, Jie Song, Heng Jin, Dingwei Yang, Xiaoqin Guo, Haojun Fan, Qi Lv   +11 more
wiley   +1 more source

Identification of Prothrombin Belgrade Variant in a Mexican–American Family with Recurrent Deep Vein Thrombosis

TH Open
A rare prothrombin variant (c.1787G > A, p.Arg596Gln), also known as the prothrombin Belgrade variant, has been associated with an increased predisposition to thrombosis through resistance to antithrombin.
Émile Moura Coelho da Silva, Natalie Montanez, Miguel Escobar   +2 more
doaj   +1 more source

Prothrombin and Haemorrhage [PDF]

BMJ, 1954
A C, DONALD, R B, HUNTER, G R, TUDHOPE, W, WALKER, I, WHITTON   +4 more
openaire   +2 more sources

Conditions determining end products of prothrombin activation in serum

, 1962
When blood clots normally such a small amount of prothrombin and small quantity of accelerators remain in the hour-old serum that the prothrombin consumption test is prolonged.
R. W. Monto, M. K. Buscaglia, S. A. Johnson, J. L. McKenna   +3 more
core   +1 more source

Portal vein peak systolic velocity is a useful noninvasive predictor of high‐risk varices in biliary atresia

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Portal vein (PV) flow velocity is considered an indicator of portal hypertension. However, few studies have evaluated the predictive performance of PV flow velocity for high‐risk varices (HRV) in children with biliary atresia (BA). In this study, we evaluated the predictive performance of PV peak systolic velocity (PSV) for HRV in ...
Tomoya Fukuoka, Hiroyo Ishii, Emi Ito, Yuki Matsuoka, Yoshikazu Miura, Takeshi Kimura, Kazuhiko Bessho, Takehisa Ueno, Yasuji Kitabatake   +8 more
wiley   +1 more source

Effects of Protamine Reversal on Coagulation Parameters After High-Dose Heparin Administration in Percutaneous Hepatic Chemosaturation Intervention

Clinics and Practice
Background: Intravenous protamine administration for heparin reversal after percutaneous hepatic chemosaturation intervention is generally recommended, but its effectiveness on coagulation parameters remains unclear.
Michael Metze, Silke Zimmermann, Holger Kirsten, Robert Werdehausen, Rhea Veelken, Florian van Bömmel, Timm Denecke, Hans-Jonas Meyer, Sebastian Ebel, Manuel Florian Struck   +9 more
doaj   +1 more source