Results 101 to 110 of about 162,806 (305)

Homozygous prothrombin gene mutation and ischemic cerebrovascular disease: A case report and review of literature

Journal of Applied Hematology, 2019
This report describes a 32-year-old Saudi nonsmoker man who presented to the emergency department with a history of left-sided hemiparesis and no risk factors for cerebral stroke being reported, except type II diabetes mellitus.
Mohammed AlSheef, Mohammed S Almohaya, Arshad M Mian, Saad Mohammed Aljuhayyim   +3 more
doaj   +1 more source

Chronic Liver Disease: Assessing Inflammation and Fibrosis Using Three‐Dimensional MR Elastography With Same‐Day Biopsy in a Prospective Cohort

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Three‐dimensional (3D) MR elastography (MRE) derives viscoelastic parameters that may reflect inflammation, but their frequency dependence and the influence of steatosis on inflammation grading and fibrosis staging remain unclear. Purpose To investigate 3D multifrequency MRE for assessing hepatic inflammation, fibrosis stage across ...
Shan Cai, Christian Simonsson, Markus Karlsson, Wile Balkhed, Jens Tellman, Simone Ignatova, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Wolf C. Bartholomä, Nils Dahlström, Peter Lundberg   +11 more
wiley   +1 more source

The role of genetic hemostasis gene variants in the development of venous thrombosis in patients with atherosclerosis after COVID-19 infection

Инфекция и иммунитет
Introduction. The new coronavirus infection (COVID-19) is one of the most important problems in modern medicine. One of the etiopathogenetic COVID-19 arms is presented by a disorder in the hemostasis system, which can be associated with emerging ...
O. A Perevezentsev, I. S. Mamedov, D. V. Burtsev   +2 more
doaj   +1 more source

Success of transition to adult care in patients with pediatric‐onset chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Previous studies on chronic pediatric‐onset conditions have highlighted the risks of loss to follow‐up, disease progression, or therapeutic nonadherence during transition. However, very few studies have focused on liver diseases.
Sarah Mongbo, Valérie Canva, Sébastien Dharancy, Guillaume Lassailly, Alexandre Louvet, Philippe Mathurin, Nassima Ramdane, Frédéric Gottrand, Madeleine Aumar   +8 more
wiley   +1 more source

The effect of prothrombin, the precursor of thrombin, on the proliferation and migration of colorectal cancer cells [PDF]

Archives of Biological Sciences
Thrombotic disorders are some of the main comorbidities in cancer patients. So far, research has indicated that thrombin, a key regulator of hemostasis, contributes to cancer progression.
Cumbo Marija, Dunjić-Manevski Sofija, Gvozdenov Maja, Mitić Martina Mia, Đorđević Valentina, Tomić Branko   +5 more
doaj   +1 more source

The needle study: Machine learning as a new method for case‐finding in celiac disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite a well‐defined diagnostic work‐up, uncertainties persist regarding celiac disease (CeD) detection strategies in the general population. Machine learning (ML) algorithms offer promise in aiding medical decision‐making on clinical data.
Chiara Maria Trovato, Monica Montuori, Maria Ludovica Costanzo, Giusy Russo, Cosimo Ruggiero, Danila Volpe, Francesca Ferretti, Antonella Diamanti, Carlo Ciliberto, Salvatore Oliva   +9 more
wiley   +1 more source

Inherited thrombophilia in a Han Chinese family caused by prothrombin Ile441Met mutation

Research and Practice in Thrombosis and Haemostasis
Background: Inherited thrombophilia (IT) is a genetically determined predisposition to thromboembolic events. Beyond the well-known G20210A mutation, there has been limited research on other prothrombin mutations in the Chinese population.
Si-Yuan Wen, Fei-Fei Chen, Ji-De Chen, Pan Tao, Chi Meng, Jing Huang, Xin Kang, Wei Chen, Chang-Qing Zhou   +8 more
doaj   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Construction of a Non‐Invasive Predictive Model Based on PIVKA‐II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley   +1 more source

A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

Clinical Case Reports
Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant.
Cecilia Augustsson, Knut Taxbro, Karin Strandberg, Eva Zetterberg   +3 more
doaj   +1 more source