Results 81 to 90 of about 134,214 (298)

Prothrombin complex concentrates: an update.

open access: yes, 2010
Prothrombin complex concentrates: an ...
LIPPI, Giuseppe, Franchini M
core   +1 more source

Frequency of Factor V Leiden and Prothrombin Polymorphism in South of Iran [PDF]

open access: yesIranian Journal of Medical Sciences, 2009
Normal hemostasis requires balanced regulation of prothromboticand antithrombotic factors. Inherited alteration of factor Vand prothrombin gene, the G20210A mutation, increases the resistanceof factor V to degradation and booster production ofprothrombin
Javad Dehbozorgian   +6 more
doaj  

Generation of Prothrombin Activity With Mitochondria or With Cathepsin

open access: yes, 1957
Prothrombin activity can be regenerated from ‘inactive’ prothrombin in the presence of either liver mitochondria or cathepsin concentrates obtained from spleen or liver. This regeneration of prothrombin occurs more rapidly near ph 7.9.
Marion I. Barnhart
core   +1 more source

Activation of prothrombin, fibrinogen, and TAFI.

open access: yes, 2013
(A) MASP-1 induced generation of the activation marker prothrombin fragment F1+2 in normal plasma. (B) Dose- and time-dependent prothrombin cleavage by MASP-1 was confirmed using purified proteins.
Verena Schroeder (325642)   +5 more
core   +1 more source

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

open access: yesiMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao   +10 more
wiley   +1 more source

Hepatic Encephalopathy and Age Were Assessed to Ameliorate the Underestimation of the Model for End‐Stage Liver Disease Score in Patients With Acute‐on‐Chronic Liver Failure

open access: yesiNew Medicine, EarlyView.
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen   +5 more
wiley   +1 more source

The Association between Preeclampsia and Defined Polymorphisms in Prothrombin and Coagulation Factor V Genes [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2016
Background & Aims: Preeclampsia is one of the complications of pregnancy and a major cause of maternal mortality. Since, hypercoagulation is one of the risk factors, defined polymorphisms of V and II coagulation factors (G1691A and G20210A) may increase ...
Zohreh Salari   +3 more
doaj  

Homozygous prothrombin gene mutation and ischemic cerebrovascular disease: A case report and review of literature

open access: yesJournal of Applied Hematology, 2019
This report describes a 32-year-old Saudi nonsmoker man who presented to the emergency department with a history of left-sided hemiparesis and no risk factors for cerebral stroke being reported, except type II diabetes mellitus.
Mohammed AlSheef   +3 more
doaj   +1 more source

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