Results 81 to 90 of about 123,279 (307)
, 1981 Clotting and chromogenic assays utilising Echis carinatus venom were set up to determine the total prothrombin-related material (PRM) in plasma and liver fractions.
Linda Jane. Beecroft (7700789)
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Congenital prothrombin deficiency: an update [PDF]
, 2013 Prothrombin (factor II [FII]) deficiency is a rare inherited coagulation disorder, having a prevalence of approximately 1 in 2,000,000. Two phenotypes can be distinguished: (1) true hypoprothrombinemia (type I deficiency), characterized by ...
De Cristofaro, Raimondo +2 more
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British Journal of Clinical Pharmacology, EarlyView.Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind +7 more
wiley +1 more source
AUTOPROTHROMBIN C: A SECOND ENZYME FROM PROTHROMBIN [PDF]
, 1962 In addition to thrombin, there is another derivative of prothrombin which is an end product of prothrombin activation. It is an accelerator of prothrombin activation, and is called autoprothrombin C. The activity develops from purified bovine prothrombin
Walter H. Seegers, Ewa Marciniak
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson +8 more
wiley +1 more source
Cellular site for prothrombin synthesis [PDF]
, 1960 The cell type responsible for synthesis of any of the trace plasma proteins concerned in blood coagulation has not been identified before. In this study the fluorescent antibody technique was used to find out the cellular site for prothrombin synthesis.
Marion I. Barnhart
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot +7 more
wiley +1 more source
Prothrombin Activation Is Increased among Asymptomatic Carriers of the Prothrombin G20210A and Factor V Arg506Gln Mutations [PDF]
, 2000 SummaryThe risk of venous thrombosis is increased in individuals who carry specific genetic abnormalities in blood coagulation proteins. Among Caucasians, the prothrombin G20210A and factor V Arg506Gln (FV R506Q) mutations are the most prevalent defects ...
Kenneth Bauer +7 more
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Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
BMEMat, EarlyView.The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Chicken prothrombin, thrombin, and fibrinogen [PDF]
, 1961 Avian blood coagulation studies revealed the mean one-stage prothrombin time of plasma from 100 chickens, 10 weeks of age, as determined with chicken brain thromboplastin, to be 11.4 seconds, compared with 10–300 seconds found by other workers; the mean
D. C. Triantaphyllopoulos, C. H. Bigland
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