Results 81 to 90 of about 130,862 (286)

Engineered molecular diagnostic strategies for hepatocellular carcinoma: Integrating flexible photonic barcodes, liquid biopsies, and AI‐enhanced sensing platforms

open access: yesFlexMat, EarlyView.
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue   +5 more
wiley   +1 more source

The Association between Preeclampsia and Defined Polymorphisms in Prothrombin and Coagulation Factor V Genes [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2016
Background & Aims: Preeclampsia is one of the complications of pregnancy and a major cause of maternal mortality. Since, hypercoagulation is one of the risk factors, defined polymorphisms of V and II coagulation factors (G1691A and G20210A) may increase ...
Zohreh Salari   +3 more
doaj  

Homozygous prothrombin gene mutation and ischemic cerebrovascular disease: A case report and review of literature

open access: yesJournal of Applied Hematology, 2019
This report describes a 32-year-old Saudi nonsmoker man who presented to the emergency department with a history of left-sided hemiparesis and no risk factors for cerebral stroke being reported, except type II diabetes mellitus.
Mohammed AlSheef   +3 more
doaj   +1 more source

Thrombophilia in pregnancy: a systematic review [PDF]

open access: yes, 2006
Growing evidence suggests that thrombophilia is associated with venous thromboembolism (VTE) and adverse pregnancy outcomes. However, methodological limitations have made it difficult to obtain a clear overview of the overall risks.
Lowe, G.D.O.   +11 more
core   +1 more source

The role of genetic hemostasis gene variants in the development of venous thrombosis in patients with atherosclerosis after COVID-19 infection

open access: yesИнфекция и иммунитет
Introduction. The new coronavirus infection (COVID-19) is one of the most important problems in modern medicine. One of the etiopathogenetic COVID-19 arms is presented by a disorder in the hemostasis system, which can be associated with emerging ...
O. A Perevezentsev   +2 more
doaj   +1 more source

Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen‐linked hepatic–reproductive crosstalk

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Severe surgically confirmed endometriosis was associated with a lower prevalence of steatotic liver disease than non‐severe disease. Higher estradiol levels may partly explain this inverse hepatic–reproductive association, supporting integrated gynecologic and hepatologic risk assessment.
Jung Hyun Park   +5 more
wiley   +1 more source

Inherited thrombophilia in a Han Chinese family caused by prothrombin Ile441Met mutation

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Inherited thrombophilia (IT) is a genetically determined predisposition to thromboembolic events. Beyond the well-known G20210A mutation, there has been limited research on other prothrombin mutations in the Chinese population.
Si-Yuan Wen   +8 more
doaj   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

The effect of prothrombin, the precursor of thrombin, on the proliferation and migration of colorectal cancer cells [PDF]

open access: yesArchives of Biological Sciences
Thrombotic disorders are some of the main comorbidities in cancer patients. So far, research has indicated that thrombin, a key regulator of hemostasis, contributes to cancer progression.
Cumbo Marija   +5 more
doaj   +1 more source

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