Results 71 to 80 of about 190,185 (400)

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

Identification of Prothrombin Belgrade Variant in a Mexican-American Family with Recurrent Deep Vein Thrombosis. [PDF]

open access: yesTH Open
A rare prothrombin variant (c.1787G > A, p.Arg596Gln), also known as the prothrombin Belgrade variant, has been associated with an increased predisposition to thrombosis through resistance to antithrombin.
Moura Coelho da Silva É   +2 more
europepmc   +2 more sources

Polymorphisms in FVL, prothrombin, and MTHFR genes in samples tested for thrombophilia in Saudi Arabia

open access: yesRomanian Journal of Laboratory Medicine
Thrombophilia is a multifactorial condition influenced by both genetic and acquired risk factors and plays a key role in the development of venous thromboembolism (VTE).
Alhuthali Hayaa Moeed   +9 more
doaj   +1 more source

Risk Factors for Small‐for‐Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living‐Donor Liver Transplantation

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa   +6 more
wiley   +1 more source

Anti-Phosphatidylserine, Anti-Prothrombin, and Anti-Annexin V Autoantibodies in Antiphospholipid Syndrome: A Real-Life Study

open access: yesDiagnostics, 2023
The antiphospholipid antibodies (aPL) increase the risk of developing thrombotic events and may coexist with a variety of autoimmune diseases. They can be detected chronically or temporarily in patients with infectious diseases, during drug therapy, or ...
Daniele Roselli   +5 more
doaj   +1 more source

Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro.

open access: yesThrombosis Research, 2014
INTRODUCTION Anticoagulation therapies carry a risk of bleeding; reversal agents may be beneficial in cases of severe bleeding even for anticoagulants with a relatively short half-life, such as the oral factor Xa inhibitor rivaroxaban.
E. Perzborn   +3 more
semanticscholar   +1 more source

Efficacy and Safety of a Simple Auxiliary Liver Suspension Device in Complex Laparoscopic Hepatectomy: A Multicenter Randomized Clinical Trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Purpose To evaluate the efficacy and safety of a novel auxiliary liver suspension device in complex laparoscopic hepatectomy. Methods A total of 253 patients with hepatocellular carcinoma (HCC) undergoing complex laparoscopic hepatectomy at the Third Affiliated Hospital of Naval Medical University, Sichuan Provincial People's Hospital, and ...
Xiao‐Ying Zhu   +9 more
wiley   +1 more source

Induction of prothrombin synthesis by prothrombin fragments. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1981
The mechanisms by which blood levels of prothrombin (PT) are regulated in the vitamin K-sufficient state are unknown. We have studied PT synthesis by Reuber H-35 rat hepatoma cells exposed to vitamin K and [3H]leucine in serum-free cultures. Administration to the culture system of exogenous bovine PT and rat PT was characterized by increases in ...
C B, Graves   +4 more
openaire   +2 more sources

Emergency Cholecystectomy in Patients Classified as High Risk According to the Tokyo Guidelines 2018: A Real‐World Analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Emergency cholecystectomy was evaluated in patients with acute cholecystitis classified as non‐recommended for surgery by the Tokyo Guidelines 2018. Major postoperative complications, rather than mortality, better reflected operative risk. Physiological instability, particularly ASA‐PS ≥ 3 and shock status, identified high‐risk patients, suggesting ...
Satoshi Mii   +9 more
wiley   +1 more source

Prevalence of hereditary risk factors for thrombophilia in Belém, Brazilian Amazon

open access: yesGenetics and Molecular Biology, 2006
Different risk factors for venous thromboembolism (VTE) have been identified, including hereditary abnormalities in the mechanisms of coagulation and fibrinolysis.
France Keiko Nascimento Yoshioka   +4 more
doaj   +1 more source

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