Results 51 to 60 of about 123,279 (307)

Is perioperative point-of-care prothrombin time testing accurate compared to the standard laboratory test? [PDF]

open access: yes, 2009
There is no accepted way of measuring prothrombin time without time loss for patients undergoing major surgery who are at risk of intraoperative dilution and consumption coagulopathy due to bleeding and volume replacement with crystalloids or colloids ...
Lord, Sarah J   +7 more
core   +1 more source

The frequency of β-globin gene haplotypes, α-thalassemia and genetic polymorphisms of methylenetetrahydrofolate reductase, factor V Leiden and prothrombin genes in children with sickle cell disease in Rio de Janeiro, Brazil Frequência dos haplótipos da globina beta, da talassemia alfa e dos polimorfismos genéticos dos genes da metilenotetrahidrofolato redutase, do fator V Leiden e da protrombina em crianças com doença falciforme no Rio de Janeiro, Brasil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2010
A freqüência dos haplótipos beta S e beta C do gene da globina e a prevalência de talassemia alfa e de mutações nos genes da metilenotetrahidrofolato redutase (MTHFR-C677T), do fator V de Leiden e da protrombina (G20210A) foi estudada em crianças com ...
Isaac L. Silva Filho   +3 more
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

open access: yesAdvanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh   +11 more
wiley   +1 more source

Polymorphisms in the Prothrombin Gene and their Association with Plasma Prothrombin Levels [PDF]

open access: yes, 2001
SummaryTo find genetic causes of high plasma prothrombin levels, an established prothrombotic risk factor, we searched for sequence variations in the prothrombin gene.
A. van Hylckama Vlieg   +4 more
core   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

open access: yesAdvanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung   +6 more
wiley   +1 more source

Partial activation of prothrombin and generation of prothrombin-R with cathepsin B [PDF]

open access: yes, 1960
Maximal yields of prothrombin-R were readily produced from a number of prothrombin derivatives when these were mixed with purified cathepsin B at pH 7.9.
Marion I. Barnhart
core   +1 more source

Development of a paper-based lateral flow Prothrombin assay [PDF]

open access: yes, 2022
Disorders of haemostasis result in both excessive bleeding and clotting and are a major global cause of morbidity and mortality, particularly in the developing world. A small number of simple tests can be used to screen and monitor for such dysfunctions,
Killard, Anthony   +4 more
core   +2 more sources

Polymorphisms in FVL, prothrombin, and MTHFR genes in samples tested for thrombophilia in Saudi Arabia

open access: yesRomanian Journal of Laboratory Medicine
Thrombophilia is a multifactorial condition influenced by both genetic and acquired risk factors and plays a key role in the development of venous thromboembolism (VTE).
Alhuthali Hayaa Moeed   +9 more
doaj   +1 more source

Protein Corona Formation on Soft Nanocarriers Under Biomimetic Circulatory Flow

open access: yesAdvanced Materials Interfaces, EarlyView.
A biomimetic venous circulation system is developed to study protein corona formation on soft nanocarriers under physiological shear. Liposomes, PLGA nanoparticles, and lipid‐polymer hybrid nanoparticles acquire largely shared but material‐dependent protein coronas that alter surface properties and suppress cellular uptake, highlighting the importance ...
Anamarija Nikoletić   +7 more
wiley   +1 more source

Evolution of prothrombin: Isolation and characterization of the cDNAs encoding chicken and hagfish prothrombin [PDF]

open access: yes, 1994
The cDNA sequences of chicken and hagfish prothrombin have been determined. The sequences predict that prothrombin from both species is synthesized as a prepro-protein consisting of a putative Gla domain, two kringle domains, and a two-chain protease ...
Banfield, David K.   +3 more
core   +1 more source

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