Results 61 to 70 of about 123,279 (307)
FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
Advanced Science, EarlyView.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
USE in prothrombin 3′-UTR influences the selection of the natural prothrombin cleavage site [PDF]
, 2011 Copyright information:Taken from "The relationship between the prothrombin upstream sequence element and the G20210A polymorphism: the influence of a competitive environment for mRNA 3′-end formation"Nucleic Acids Research 2005;33(3):1010-1020.Published ...
Jeffrey Wilusz (6673) +3 more
core +1 more source
Induction of prothrombin synthesis by prothrombin fragments. [PDF]
Proceedings of the National Academy of Sciences, 1981 The mechanisms by which blood levels of prothrombin (PT) are regulated in the vitamin K-sufficient state are unknown. We have studied PT synthesis by Reuber H-35 rat hepatoma cells exposed to vitamin K and [3H]leucine in serum-free cultures. Administration to the culture system of exogenous bovine PT and rat PT was characterized by increases in ...
C B, Graves +4 more
openaire +2 more sources
Advanced Science, EarlyView.An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu +8 more
wiley +1 more source
Prothrombin G20210A is a bifunctional gene polymorphism [PDF]
, 2002 The G20210A polymorphism has been shown to alter the efficiency of prothrombin mRNA processing. Here we show that the G20210A mutation also alters prothrombin mRNA stability.
Mythily Sachchithananthan +9 more
core +1 more source
Prevalence of hereditary risk factors for thrombophilia in Belém, Brazilian Amazon
Genetics and Molecular Biology, 2006 Different risk factors for venous thromboembolism (VTE) have been identified, including hereditary abnormalities in the mechanisms of coagulation and fibrinolysis.
France Keiko Nascimento Yoshioka +4 more
doaj +1 more source
Diagnostics, 2020 Colorectal cancer (CRC) is the second cause of death in men and the third in women. This work deals with the study of the low molecular weight protein fraction of sera from patients who underwent surgery for CRC and who were followed for several years ...
Maider Beitia +8 more
doaj +1 more source
Diagnostics, 2023 The antiphospholipid antibodies (aPL) increase the risk of developing thrombotic events and may coexist with a variety of autoimmune diseases. They can be detected chronically or temporarily in patients with infectious diseases, during drug therapy, or ...
Daniele Roselli +5 more
doaj +1 more source
Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds
Advanced Science, EarlyView.This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng +14 more
wiley +1 more source
Prothrombin G20210A mutation in Turkish children with thrombosis and the frequency of prothrombin C20209T [PDF]
, 2005 The prothrombin G20210A mutation has been described as the second most common genetic risk factor in thrombotic patients. Recently a new prothrombin gene variant namely prothrombin C20209T has also been found to be associated with thrombosis.
Gurgey, A +4 more
core +1 more source