Results 41 to 50 of about 123,279 (307)
Prothrombin Complex Concentrate (Beriplex P/N)-related Renal and Cerebral Infarctions in a Patient with Warfarin-associated Intracerebral Hemorrhage [PDF]
, 2017 A 45-year-old man receiving warfarin treatment suffered from an intracerebral hemorrhage. Four-factor prothrombin complex concentrate (PCC) was administered to correct coagulopathy.
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PathophysiologyBackground: Thrombophilia, a predisposition to develop blood clots, is very common and can have serious sequelae. Aim: This study aimed to determine the prevalence of three thrombophilia-related genetic variants—factor V Leiden (FVL), prothrombin (F2 ...
Sapha Shibeeb +5 more
doaj +1 more source
The Conversion of Bovine Abnormal Prothrombin into Prothrombin [PDF]
Thrombosis and Haemostasis, 1977 In order to characterize the enzyme system which converts abnormal prothrombin (PIVKA-II) in prothrombin we prepared liver cell-free extracts from normal healthy cows. The enzyme system devoid of either precursor or prothrombin was isolated by differential centrifugation and partly purified with the aid of column chromatography.The carboxylation of ...
C. Vermeer, B.A. M. Soute, H.C. Hemker
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
The development of a novel native prothrombin assay for the more efficient management of oral anticoagulation therapy [PDF]
, 2004 Disturbances of the natural balance between pro-coagulant and anticoagulant systems, due to hereditary or acquired factors may result in haemorrhagic or thrombotic diseases.
Sylvester, Adrian Jose
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PROTHROMBIN SYNTHESIS: AN EXAMPLE OF HEPATIC FUNCTION [PDF]
, 1965 Prothrombin, a plasma protein valuable in blood coagulation, appears to be produced exclusively by liver parenchymal cells. Immunuofluorescent procedures were applied to various organs from bovine, canine and human sources.
MARION I. BARNHART
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Gestational complications of the prothrombin G20210A mutation related to prothrombin activity [PDF]
, 2020 Aim: to study the association between prothrombin activity in the blood plasma and gestational complications in women with the prothrombin G20210A mutation.Materials and methods. A prospective clinical cohort study including 290 pregnant women aged 18 to
N. N. Yasafova +5 more
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Animals, 2022 The Asian elephant population is continuously declining due to several extrinsic reasons in their range countries, but also due to diseases in captive populations worldwide.
Sónia A. Jesus +8 more
doaj +1 more source
Role of Thrombin in Central Nervous System Injury and Disease
Biomolecules, 2021 Thrombin is a Na+-activated allosteric serine protease of the chymotrypsin family involved in coagulation, inflammation, cell protection, and apoptosis. Increasingly, the role of thrombin in the brain has been explored. Low concentrations of thrombin are
Nathan A. Shlobin +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández +14 more
wiley +1 more source