Health Science Reports, 2022 Background and aims To provide a fair estimate of the prevalence of factor V Leiden (FVL) (G1691A), prothrombin (G20210A), and MTHFR (C677T) mutations in the Greek population.
Alkistis Raptopoulou +7 more
doaj +1 more source
Association of Factor II G20210A, Factor V G1691A and methylenetetrahydrofolate reductase C677T gene polymorphism with different forms of myocardial infarction: ST segment elevation and non-ST segment elevation [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. Coagulation Factor II G20210A and Factor V G1691A variants are moderately associated with coronary artery disease. Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene C677T is associated with myocardial infarction (MI) in ...
Ćućuz-Jokić Milica +4 more
doaj +1 more source
Anaesthesia, 2020 There is equipoise regarding the use of prothrombin complex concentrate vs. fresh frozen plasma in bleeding patients undergoing cardiac surgery. We performed a pilot randomised controlled trial to determine the recruitment rate for a large trial ...
L. Green +14 more
semanticscholar +1 more source
Blood coagulation factors and platelet response to drug‐induced hepatitis and hepatosis in rats
Animal Models and Experimental Medicine, 2023 Background Knowing the variability of blood coagulation responses to liver damage of different origins can provide a key to curing liver tissues or to mitigating treatment side effects.
Daria Korolova +8 more
doaj +1 more source
Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana +4 more
doaj +1 more source
Frontiers in Medicine, 2018 Coagulation factor II, or prothrombin, is a multi-domain glycoprotein that is essential for life and a key target of anticoagulant therapy. In plasma, prothrombin circulates in two forms at equilibrium, “closed” (~80%) and “open” (~20%), brokered by the ...
Mathivanan Chinnaraj +2 more
doaj +1 more source
Reference materials (RMs) for analysis of the human factor II (prothrombin) gene G20210A mutation [PDF]
, 2005 The Scientific Committee of Molecular Biology Techniques (C-MbT) in Clinical Chemistry of the IFCC has initiated a joint project in co-operation with the European Commission, Joint Research Centre, Institute of Reference Materials and Measurements to ...
Tosetto, Alberto +64 more
core +1 more source
Missense mutations in the gene encoding prothrombin corresponding to Arg596 cause antithrombin resistance and thrombomodulin resistance [PDF]
, 2016 Antithrombin (AT) and thrombomodulin (TM) play important roles in the process of natural anticoagulation in vivo. Recently, we reported that the prothrombin Yukuhashi mutation (p.Arg596Leu) was associated with AT and TM resistance-related thrombophilia ...
Saito, H. +9 more
core +1 more source
Thrombophilic molecular markers in young patients (<40 years) with coronary artery disease
Indian Journal of Pathology and Microbiology, 2012 Background: There has been an alarming rise in the incidence of coronary artery disease (CAD) in India especially involving the age group of less than 45 years. In recent past, various studies focused on hemostatic aspects of CAD, but could not determine
Mingma Sherpa +2 more
doaj +1 more source
Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]
, 2010 The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Hanot, Camille +11 more
core +1 more source