Results 91 to 100 of about 134,214 (298)

Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K-1) in severe acute liver disease [PDF]

, 2005
Background/Aims: In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K-1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy ...
Pereira, SP, David Rowbotham, Stephen P. Pereira, Sarah Fitt, Fitt, S, Pereira, S P, Wendon, J, Roger Williams, Williams, R, Julia Wendon, Rowbotham, D, Martin J. Shearer, Shearer, MJ, Shearer, M J   +13 more
core   +1 more source

Hospital Volume and Operative Mortality in Pancreaticoduodenectomy and Hepatectomy: Analysis of the National Clinical Database in Japan

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose This study evaluated the association between institutional advanced hepatobiliary‐pancreatic (HBP) surgical volume and operative mortality for pancreaticoduodenectomy (PD) and advanced hepatectomy using data from the Japanese National Clinical Database.
Yoshitaro Shindo, Hideki Endo, Hiroyuki Yamamoto, Hidenori Takahashi, Shigeru Marubashi, Atsushi Nanashima, Itaru Endo, Hideki Ueno, Ken Shirabe, Masafumi Nakamura, Hiroaki Nagano, Masayuki Ohtsuka   +11 more
wiley   +1 more source

The role of genetic hemostasis gene variants in the development of venous thrombosis in patients with atherosclerosis after COVID-19 infection

Инфекция и иммунитет
Introduction. The new coronavirus infection (COVID-19) is one of the most important problems in modern medicine. One of the etiopathogenetic COVID-19 arms is presented by a disorder in the hemostasis system, which can be associated with emerging ...
O. A Perevezentsev, I. S. Mamedov, D. V. Burtsev   +2 more
doaj   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Pancreas–Intestine Composite Transplantation for Simultaneous Loss of Pancreatic and Intestinal Function (With Video)

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreas–intestine composite transplantation (PITx) is a therapeutic option for patients with irreversible loss of both pancreatic and intestinal function. We report a case of PITx in a 16‐year‐old male who developed fulminant Type 1 diabetes mellitus complicated by non‐occlusive mesenteric ischemia, resulting in extensive intestinal necrosis.
Kei Yamane, Takashi Ito, Takayuki Anazawa, Junji Fujikura, Makoto Okabe, Satoshi Ishida, Koki Kurahashi, Masaaki Hirata, Hiroshi Kawamoto, Hiroto Nishino, Asahi Sato, Tomoaki Yoh, Hidenobu Kojima, Shinya Okumura, Takahiro Nishio, Daisuke Ueda, Hirofumi Hirao, Yuki Masano, Shoichi Kageyama, Katsunori Sakamoto, Satoshi Ogiso, Kazuyuki Nagai, Yoichiro Uchida, Takamichi Ishii, Etsuro Hatano   +24 more
wiley   +1 more source

Inherited thrombophilia in a Han Chinese family caused by prothrombin Ile441Met mutation

Research and Practice in Thrombosis and Haemostasis
Background: Inherited thrombophilia (IT) is a genetically determined predisposition to thromboembolic events. Beyond the well-known G20210A mutation, there has been limited research on other prothrombin mutations in the Chinese population.
Si-Yuan Wen, Fei-Fei Chen, Ji-De Chen, Pan Tao, Chi Meng, Jing Huang, Xin Kang, Wei Chen, Chang-Qing Zhou   +8 more
doaj   +1 more source

Concept of a Common Protein Moiety, Containing Disulfide Bonds, in Prothrombin, Prothrombin Derivative (Autoprothrombin) and Thrombin

, 1955
With a recently devised argentometric amperometric method, disulfide was demonstrated in biothrombin, citrate thrombin and prothrombin derivative (autoprothrombin) in the same quantity (43 µm/100 mg N) as that present in prothrombin.
E. D. Warner, John R. Carter
core   +1 more source

Improvements of the method for the preparation of an artificial prothrombin reagent [PDF]

, 1978
Improvements of a method to prepare a [bovine] prothrombin-free reagent for the 1-stage determination of prothrombin were discussed.
Vermeer, C., Soute, B.A.M., Hemker, H.C.
core   +1 more source

Safety of Continuing Single‐Agent Antithrombotic Therapy During Emergency Cholecystectomy for Acute Cholecystitis: An Overlap‐Weighted Propensity Score Analysis With the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Optimal perioperative antithrombotic therapy (ATT) management during emergency cholecystectomy for acute cholecystitis remains controversial. We examined whether continuing single‐agent ATT is associated with hemorrhagic risk compared with no ATT.
Takeshi Tadokoro, Tomoyuki Abe, Masateru Yamamoto, Yuki Imaoka, Naruhiko Honmyo, Ryosuke Nakano, Seiichi Shimizu, Shintaro Kuroda, Hiroyuki Tahara, Masahiro Ohira, Tsuyoshi Kobayashi, Masakazu Hashimoto, Ko Oshita, Hiroshi Sakai, Michinori Hamaoka, Naoki Tanimine, Masashi Inoue, Tomoyuki Akita, Hideki Ohdan, Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)   +19 more
wiley   +1 more source

The effect of prothrombin, the precursor of thrombin, on the proliferation and migration of colorectal cancer cells [PDF]

Archives of Biological Sciences
Thrombotic disorders are some of the main comorbidities in cancer patients. So far, research has indicated that thrombin, a key regulator of hemostasis, contributes to cancer progression.
Cumbo Marija, Dunjić-Manevski Sofija, Gvozdenov Maja, Mitić Martina Mia, Đorđević Valentina, Tomić Branko   +5 more
doaj   +1 more source