Results 91 to 100 of about 123,279 (307)
Prothrombin Time, an Indicator for Psoriasis Activity: A Case - Control Study
Iranian South Medical Journal, 2020 Background: Psoriasis is a common chronic and recurrent inflammatory skin disorder related to the immune system and characterized by the rapid growth of skin cells.
Majid Morovati-Sharifabad +2 more
doaj
Clinical Pharmacology &Therapeutics, EarlyView.Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu +6 more
wiley +1 more source
Medicina, 2019 Background and Objective: Evidence indicates that genetic factors may be involved in the risk of ischemic stroke (IS). The aim of this study was to assess the effect of genetic polymorphisms located in exons or untranslated regions of MTHFR as well as FV
Seyed Mehdi Hashemi +7 more
doaj +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is a serious illness in which more than half of all deaths are due to malnutrition. Critically low energy and protein intake are known causes of massive weight loss, whereas micronutrient deficiencies due to a low‐calorie food pattern remain poorly characterized in children with AN. Micronutrient deficiencies in
Zenaida Iordan +6 more
wiley +1 more source
Antigenic Properties of Purified Bovine Prothrombin [PDF]
, 1956 Purified bovine prothrombin preparations were found to produce immune serum in rabbits. This immune serum possessed precipitating antibodies capable of specific reaction with these preparations.
Walter H. Seegers, Paul Halick
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ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
Activation of Prothrombin With Thrombin [PDF]
, 1958 Mixtures were made consisting of purified prothrombin as substrate (1200 u/ml) and purified thrombin as activator (83 u/ml). The calcium concentration was 0.027 m and the pH 7.2.
Walter H. Seegers +2 more
core +1 more source
The Determinant of the Prothrombin Time in Normal Human Plasma [PDF]
, 1958 SummaryNormal adult human plasma has a constant prothrombin time when determined under standardized conditions and with carefully prepared reagents. An explanation for this constancy is offered; namely, that a plasma factor, designated as “prothrombin ...
Armand J. Quick
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