Results 161 to 170 of about 174,020 (338)

Flow dilution effect on blood coagulation in vivo [PDF]

Enzyme reaction model of flow dilution effect on blood coagulation in ...
Hu, C.
core   +1 more source

Post‑Marketing Surveillance of the Safety and Effectiveness of Emicizumab in Japanese Patients With Congenital Haemophilia A With Inhibitors

Haemophilia, EarlyView.
ABSTRACT Introduction The bispecific monoclonal antibody emicizumab was approved for prophylactic treatment of congenital haemophilia A (HA) in Japan in 2018. Aim To monitor long‐term safety and effectiveness of emicizumab, including appropriate concomitant use of bypassing agents (BPAs), in Japanese patients with congenital HA with inhibitors who ...
Midori Shima, Katsuyuki Fukutake, Masanori Matsumoto, Yoshihiko Sugimura, Chiaki Sugita, Lyu Ji, Mika Kawano, Tadashi Matsushita   +7 more
wiley   +1 more source

Evidence for the involvement of superoxide in vitamin K-dependent carboxylation of glutamic acid residues of prothrombin [PDF]

, 1978
M. P. Esnouf, M R Green, H. Allen O. Hill, G. Brent Irvine, S. J. Walter   +4 more
openalex   +1 more source

Investigation of the Suitability of the ROTEM Assay to Measure Coagulation Potential in Blood From Patients on Concizumab Prophylaxis

Haemophilia, EarlyView.
ABSTRACT Background Rotational thromboelastometry (ROTEM) aims to measure the coagulation potential in whole blood. Concizumab, an anti‐tissue factor pathway inhibitor (TFPI) antibody for prophylaxis in haemophilia, enhances tissue factor (TF)‐initiated coagulation by preventing inhibition of activated factor X (FXa), thus increasing thrombin ...
Hermann Eichler, Nora V. Butta, Anne Riddell, Cecilia Augustsson, Marianne Kjalke, Kasper Jensen, Andrea Paramo‐Florencio, Jan Astermark, Pratima Chowdary, Victor Jiménez‐Yuste   +9 more
wiley   +1 more source

Lifetime Cost‐Utility Analysis of Emicizumab Prophylaxis in Severe Haemophilia A Without Inhibitors in China: A Markov Model Analysis

Haemophilia, EarlyView.
ABSTRACT Aim As emicizumab shares no sequence homology with factor VIII (FVIII), in patients with haemophilia A, haemostasis can be restored irrespective of the presence of FVIII inhibitors. Emicizumab, therefore, substantially improved previously available prophylactic options.
Han Bao, Christian Bührer, Ziyi Lin, Li Zhou, Yan Xia, Xiuze Jin, Jianwei Xuan   +6 more
wiley   +1 more source

Coagulation disorders after reperfusion of pancreatic allografts [PDF]

, 1993
Blumenstock, I., Büsing, M., Heimburger, N., Hopt, U. T., Jochum, Marianne, Nader, A.   +5 more
core   +1 more source

Enhancing the Evidence for Care in Underserved Bleeding Disorders Communities

Haemophilia, EarlyView.
ABSTRACT Background Major advances in haemophilia care have not translated equitably across all populations. Individuals with rare bleeding disorders (RBDs), people living in low‐ and lower‐middle‐income countries (LMICs) and women and girls with inherited bleeding disorders (WGWBD) continue to face significant diagnostic, therapeutic and research ...
Johnny Mahlangu
wiley   +1 more source

Detection of ‘antiphospholipid’ antibodies: a single chromogenic assay of thrombin generation sensitively detects lupus anticoagulants, anticardiolipin antibodies, plus antibodies bindingβ2-glycoprotein I and prothrombin [PDF]

, 2001
Yonghua Sheng, John G. Hanly, Stephen Reddel, S Kouts, Jan Guerin, Takayoshi Koike, Kenji Ichikawa, Allan Sturgess, Steven A. Krilis   +8 more
openalex   +1 more source

Pre‐Treatment Liver Stiffness Is a Stronger Predictor of Hepatocellular Carcinoma Development Than Post‐Treatment Liver Stiffness After Hepatitis C Virus Eradication

Hepatology Research, EarlyView.
Higher pre‐treatment liver stiffness measurement (LSM) values, rather than post‐treatment values, independently predicts hepatocellular carcinoma after hepatitis C virus eradication, underscoring the need for continued surveillance in patients with elevated baseline LSM.
Takuma Nakatsuka, Ryo Nakagomi, Keisuke Mabuchi, Yuki Matsushita, Tomoharu Yamada, Kazuya Okushin, Tatsuya Minami, Masaya Sato, Koji Uchino, Yotaro Kudo, Mitsuhiro Fujishiro, Kazuhiko Koike, Ryosuke Tateishi   +12 more
wiley   +1 more source

Effect of General Anesthesia on Liver and Spleen Stiffness for Predicting High‐Risk Varices in Biliary Atresia

Hepatology Research, EarlyView.
In children with biliary atresia (BA), breath‐holding during liver and spleen stiffness (LS and SS) measurement is often difficult, raising concerns about measurement reliability in the awake state. We investigated whether performing LS and SS measurements under general anesthesia—when brief ventilation pauses are possible—could improve diagnostic ...
Shinya Yokoyama, Takashi Honda, Yoji Ishizu, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Masanao Nakamura, Hiroo Uchida, Hiroki Kawashima   +11 more
wiley   +1 more source