Results 261 to 270 of about 219,903 (290)
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Preparation of bovine prothrombin complex and purified prothrombin
Thrombosis Research, 1972Abstract A simplified procedure is described for the large-scale purification of bovine prothrombin complex. The protein was adsorbed on barium carbonate, eluted with 3.5% sodium citrate solution, and fractionated with ammonium sulfate. Additionally, prothrombin was separated from autoprothrombin III (Factor X) and further purified by DEAE-cellulose ...
Walter H. Seegers, Lowell E. McCoy
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Monoclonal antibodies to prothrombin
Thrombosis Research, 1987Hybridoma technology was used for the production of murine monoclonal antibodies to bovine normal prothrombin. Hybrid cell cultures were assayed for the production of antibodies, both in the absence and presence of calcium ions, by Enzyme-Linked Immunosorbent Assay (ELISA). Antibody-producing cell lines were cloned two times and grown as ascites tumors.
Oscar Sudilovsky, Om P. Malhotra
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Prothrombin Activation in Rabbits
Thrombosis Research, 1999The suitability of rabbit prothrombin activation fragment F 1.2 as a marker for the activation of the coagulation system was tested. Monoclonal antibodies to rabbit F 1.2 were raised, and a competitive F 1.2 ELISA was developed. Within the detection limit of the ELISA, no increase in rabbit F 1.2 was detected upon recalcification of plasma, whereas ...
Martin Thoolen +6 more
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The Preparation of Prothrombin-Free Ox Plasma in the Estimation of Prothrombin
Scandinavian Journal of Clinical and Laboratory Investigation, 1953AbstractOxalated ox plasma treated with barium sulphate (2 g) per 100 ml) is suitable in the estimation of prothrombin activity by the method described by Owren. The preparation is simple and cheapqr than the original procedure.
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2007
Blood coagulation is initiated following injury to the blood vessel wall through the exposure of tissue factor, which mediates the activation of circulating factor VII. Activated factor VIIa forms a complex with tissue factor and triggers the subsequent steps in the activation of the coagulation system, ultimately culminating in the conversion of ...
Tatiana V. Byzova +4 more
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Blood coagulation is initiated following injury to the blood vessel wall through the exposure of tissue factor, which mediates the activation of circulating factor VII. Activated factor VIIa forms a complex with tissue factor and triggers the subsequent steps in the activation of the coagulation system, ultimately culminating in the conversion of ...
Tatiana V. Byzova +4 more
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New Prothrombin Mutation (Arg596Trp, Prothrombin Padua 2) Associated With Venous Thromboembolism
Arteriosclerosis, Thrombosis and Vascular Biology, 2016C. Bulato +6 more
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CHARACTERIZATION OF A VARIANT OF HUMAN PROTHROMBIN: PROTHROMBIN MADRID [PDF]
Annals of the New York Academy of Sciences, 1981 Marie-Claude Guillin, Annie Bezeaud
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