Machine-learning model for 30-day mortality in sepsis-associated delirium patients: A retrospective MIMIC-IV cohort study. [PDF]
Yin J, Pan X, Chen D, Zhang J, Jin G.
europepmc +1 more source
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang +15 more
wiley +1 more source
Heating up the Blunts: Prothrombin Activation, with Factor Va as an Obligate Cofactor, Is the Dominant Procoagulant Mechanism of Blunt-Nosed Viper Venoms (<i>Macrovipera</i> Species). [PDF]
Champagne PS, Seneci L, Fry BG.
europepmc +1 more source
RNA Analysis Uncovers Pathogenic PARN Variant in Dyskeratosis Congenita
Using WGS and RNA analysis, we identified a branch point‐disrupting variant in the PARN gene and elucidated its pathogenic molecular mechanism in a child with atypical dyskeratosis congenita presentation. ABSTRACT Dyskeratosis congenita (DC) is a rare genetic disorder caused by impaired telomere maintenance, leading to diverse clinical manifestations ...
Daria Akimova +3 more
wiley +1 more source
Application of thromboelastogram and coagulation function in evaluating coagulation status of pregnant women across different trimesters. [PDF]
Li J, Zhu J, Chen X, Wang M, Sha Y.
europepmc +1 more source
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock +7 more
wiley +1 more source
Factors Affecting the Time in Therapeutic Range of Warfarin Anticoagulation Therapy in Patients with Atrial Fibrillation. [PDF]
Luo X, Zhou Q.
europepmc +1 more source
ABSTRACT Background Coagulation screening, consisting of prothrombin time (PT) and activated partial prothrombin time (aPTT), is routinely performed in paediatrics to identify bleeding disorders or guide peri‐procedural management. We evaluated the trends in utilisation and diagnostic yield of PT and aPTT testing as part of coagulation screening in a ...
Gerard Gurumurthy +4 more
wiley +1 more source
Coagulation dysfunction in children with secondary hemophagocytic lymphohistiocytosis: a comprehensive analysis. [PDF]
Duan C +5 more
europepmc +1 more source

