Results 91 to 100 of about 17,204,946 (352)

A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs)

open access: yesUpsala Journal of Medical Sciences, 2017
Background: There is a clinical need for point-of-care (POC) methods for non-vitamin K-dependent oral anticoagulants (NOACs). We modified a routine POC procedure: Zafena’s Simple Simon™ PT-INR, a room-temperature, wet-chemistry prothrombin time method of
Tomas L. Lindahl   +3 more
doaj   +1 more source

The Fibrosis‐4 score is associated with overall mortality and severe haematological toxicity in older patients with cancer: Analysis of two prospective cohort studies

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Liver function decreases with age, affecting the metabolism of many chemotherapy drugs. For older cancer patients, however, a standardized liver status screening method is lacking. Here, Fibrosis‐4 (FIB‐4) score was investigated for its utility as a non‐invasive method in predicting treatment toxicity and mortality in cancer patients age 70
Victoire de Salins   +14 more
wiley   +1 more source

Genetic variants underlying precancerous conditions of hepatocellular carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero   +7 more
wiley   +1 more source

Effects of immune checkpoint inhibitors on the pulmonary circulation in lung cancer patients

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Immune checkpoint inhibitors (ICIs) are effective against various cancers, but as more patients receive these therapies, more immune‐related adverse events (irAEs) emerge. Recent studies have suggested that ICIs are associated with an increase in pulmonary artery diameter and the ratio between pulmonary artery diameter and aortic diameter ...
Yao Xu   +11 more
wiley   +1 more source

Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri   +8 more
wiley   +1 more source

Prothrombin Time

open access: yesDefinitions, 2020

semanticscholar   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi   +3 more
wiley   +1 more source

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