Results 101 to 110 of about 17,468,048 (391)

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, EarlyView.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

Short communication: Dynamic chemical labelling allows the measurement of the paracetamol toxicity biomarker microRNA‐122 in hospital clinical laboratories

British Journal of Clinical Pharmacology, EarlyView.
MicroRNA‐122 (miR‐122) is a sensitive biomarker for paracetamol‐induced liver injury. This study assessed the diagnostic performance of dynamic chemical labelling (DCL) combined with an immunoassay platform to quantify miR‐122 in human serum, as a proof‐of‐concept for hospital use.
Samar Alzeer, Antonio Marin‐Romero, Bárbara López‐Longarela, Juan J. Guardia‐Monteagudo, F. Javier Lopez‐Delgado, Salvatore Pernagallo, Juan J. Diaz‐Mochon, Mavys Tabraue‐Chavez, Kathleen Scullion, James W. Dear   +9 more
wiley   +1 more source

Clinical Significance of Prothrombin Time in Cholangiocarcinoma Patients with Surgeries

Canadian Journal of Gastroenterology and Hepatology, 2019
Background. Prothrombin time (PT) can predict survival in several types of malignancies. This study aims to investigate the predictive values of PT levels in patients with cholangiocarcinoma (CCA). Methods.
Hui-shan Wang, Xian-xiu Ge, Quan-peng Li, Jun-jie Nie, Lin Miao   +4 more
doaj   +1 more source

Evaluation of Coagulation Profile and Transfusion Support in Pre-eclampsia Patients: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Pre-eclampsia (PE) is an obstetric disorder characterised by high morbidity and mortality rates, yet it lacks a definitive etiology.
Sivaranjani Vijayasundaram, Kavitha Govindasamy, Anitha Thayanidhi, Arumugam Pothipillai   +3 more
doaj   +1 more source

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet, Siddhartha Mengi, David Garcia Labbé, Can Manh Nguyen, Jean‐Michel Paradis   +4 more
wiley   +1 more source

Prothrombin Time role in Head Injury & Intracranial Hematomas, A prospective Study of 325 cases

مجله كليه طب الكندي, 2012
Objective: Aimed to asses the role of PT estimation in early diagnosis and predicting the extent and the outcome of head injury with ICerH and/ or Contusion Method :PT was measured by Digiclot 818 Group –1: One hundred consecutive head injured patients ...
Ahmed A Salam Al Atraqchi, Eman Abdul Gafour   +1 more
doaj  

Nomogram for predicting bleeding events in nonvalvular atrial fibrillation patients receiving rivaroxaban: A retrospective study

Health Science Reports
Background and Aims To construct a bleeding events prediction model of nonvalvular atrial fibrillation (NVAF) patients receiving rivaroxaban. Methods We conducted a retrospective cohort study in patients with NVAF who received rivaroxaban from June 2017 ...
Chang Cao, Yijiao Xu, Weiwen Jiang, Shujing Wu, Yun Shen, Xiaotong Xia, Lumin Wang, Huijun Zhang, Hongni Jiang, Xiaoyu Li, Xiaoye Li, Yanrong Ye   +11 more
doaj   +1 more source

Influence of selected patient variables and operative blood loss on six-month survival following liver transplantation. [PDF]

, 1985
A group of 118 adults who underwent primary, orthotopic transplantation of the liver over a 4-year period served as the subjects of a detailed examination of their ability to survive the first 6 months as a function of their preoperative condition.
Gillquist, WP, Gordon, RD, Iwatsuki, S, Shaw, BW, Starzl, TE, Wood, RP   +5 more
core   +1 more source

Quantitative Model‐Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation

Clinical Pharmacology &Therapeutics, EarlyView.
Milvexian, an activated factor XI inhibitor, is being evaluated in the LIBREXIA phase III program for the prevention of thrombotic events, including in patients with atrial fibrillation (LIBREXIA AF). To guide the selection of a phase III dose regimen for LIBREXIA AF, two main approaches were used: (1) population pharmacokinetics and exposure–response ...
Wangda Zhou, Emily Bozenhardt, Gregory E. Alexander, Matthew L. Zierhut, Samira Merali, Antoinette Ajavon‐Hartmann, Peter Zannikos, Hyunmoon Back, EunYoung Suh, Navin Goyal, Mahesh N. Samtani, Alexei N. Plotnikov, Chandni Valiathan   +12 more
wiley   +1 more source

Laboratory and instrumental parameters of patients with ischemic heart disease in dependence of gallbladder condition: correlational analysis

Zaporožskij Medicinskij Žurnal, 2017
The correlations of right coronary artery (RCA) diameter with gallbladder (GB) width and GB distension with the development of coronary arteries anomalies have already been described.
L. M. Strilchuk, I. B. Zhakun, Z. M. Kit, O. O. Sorokopud, M. O. Kondratyuk   +4 more
doaj   +1 more source