Results 111 to 120 of about 17,468,048 (391)

The use of fibrinogen concentrate for the management of trauma-related bleeding. A systematic review and meta-analysis [PDF]

open access: yes, 2017
Haemorrhage following injury is associated with significant morbidity and mortality. The role of fibrinogen concentrate in trauma-induced coagulopathy has been the object of intense research in the last 10 years and has been systematically analysed in ...
Franchini, Massimo   +6 more
core   +1 more source

Quantitative Systems Toxicology Predicts Ivacaftor‐Induced Oxidative Stress Contributes to CFTR Modulator Hepatotoxicity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cystic fibrosis (CF) is a chronic hereditary disease that affects tens of thousands of people worldwide. The introduction of CFTR modulator therapies such as elexacaftor/tezacaftor/ivacaftor (ETI) has significantly improved the quality of life of people with CF.
Alan Shi   +3 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]

open access: yes, 1994
Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O.   +6 more
core  

Avenues of future research in homotransplantation of the liver with particular reference to hepatic supportive procedures, antilymphocyte serum, and tissue typing [PDF]

open access: yes, 1966
Three general areas of research which bear on the developing field of liver transplantation are reviewed. These are: (1) the prospects of obtaining better immunosuppression with particular reference to heterologous antilymphocyte serum; (2) the possible ...
Anderson   +31 more
core   +1 more source

Does point of care prothrombin time measurement reduce the transfusion of fresh frozen plasma in patients undergoing major surgery? The POC-OP randomized-controlled trial

open access: yesTrials, 2009
BackgroundBleeding is a frequent complication during surgery. The intraoperative administration of blood products, including packed red blood cells, platelets and fresh frozen plasma (FFP), is often live saving.
N. Urwyler   +8 more
semanticscholar   +1 more source

A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

open access: yesClinical Case Reports
Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant.
Cecilia Augustsson   +3 more
doaj   +1 more source

The changes in the fibrinogen concentration and coagulation pathways in winter and summer in cattle [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2013
Fibrinogen is an important coagulation factor and a positive acute phase protein and its levels increases in cases of inflammation infection and stress. The present research was done to determine whether the fibrinogen concentration, prothrombin time (PT)
ameneh khoshvaghti
doaj  

Influence of different cultivars of Phoenix dactylifera L-date fruits on blood clotting and wound healing

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2018
Objective: To investigate different types of dates and medical properties of influencing blood clotting and wound healing in an animal model. Methods: Three different cultivars of dates (Ajwa, Khalas, and Fardh) were examined in-vivo, for blood clotting ...
S S Hasson   +6 more
doaj   +1 more source

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