Results 271 to 280 of about 147,027 (351)
Effects of immune checkpoint inhibitors on the pulmonary circulation in lung cancer patients
What's new? Immune checkpoint inhibitors (ICIs) are effective against various cancers, but as more patients receive these therapies, more immune‐related adverse events (irAEs) emerge. Recent studies have suggested that ICIs are associated with an increase in pulmonary artery diameter and the ratio between pulmonary artery diameter and aortic diameter ...
Yao Xu +11 more
wiley +1 more source
Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis
ABSTRACT Quantitative systems pharmacology (QSP) models offer a useful platform to integrate drug pharmacology with knowledge about biological mechanisms across multiple scales and data sources into a unified quantitative framework. This makes them invaluable to address many relevant questions in drug research and development.
Johannes Tillil +2 more
wiley +1 more source
Correlation between prothrombin time and serum ferritin level in thalassaemia patients
Nasima Sultana, Salma Sadiya
openalex +2 more sources
Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome
ABSTRACT Background Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...
Rebecca Halbgebauer +17 more
wiley +1 more source
Abstract A 5‐year‐old male neutered standard poodle, presented with recurrent gingival margin haemorrhage and associated prolongations in prothrombin time and activated partial thromboplastin time, with repeatable demonstration of clinical (bleeding) and laboratory (prothrombin time, activated partial thromboplastin time) resolution with, and relapse ...
Jenny Reeve, Aiden Pang
wiley +1 more source
Abstract A 6.5‐year‐old, spayed, female dog presented in acute respiratory distress. On admission, the dog exhibited dyspnoea, bradycardia, cyanosis and gastrointestinal signs, requiring immediate intubation and mechanical ventilation. Diagnostic evaluation revealed reduced butyrylcholinesterase activity, non‐cardiogenic pulmonary oedema, elevated ...
Sarah Hefer +6 more
wiley +1 more source
Hyalohyphomycotic chronic rhinosinusitis caused by Microascus cirrosus in a cat
Abstract A 13‐year‐old, male, neutered, indoor‐only, domestic long‐haired cat was presented with an 8‐month history of sneezing and a 2‐month history of epistaxis. Computed tomography demonstrated an irregular contrast‐enhancing soft tissue opacity within both nasal cavities and osteolysis of surrounding bony structures.
Leonel Frutuoso +4 more
wiley +1 more source

