Results 41 to 50 of about 23,181 (145)
Kinetics and Thermodynamics of Membrane Protein Folding [PDF]
Biomolecules 2014, 4(1), 354-373, 2014 Understanding protein folding has been one of the great challenges in biochemistry and molecular biophysics. Over the past 50 years, many thermodynamic and kinetic studies have been performed addressing the stability of globular proteins. In comparison, advances in the membrane protein folding field lag far behind. Although membrane proteins constitute
arxiv +1 more source
Journal of Periodontology, EarlyView.Abstract Background Periodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients.
Zhao Wang +10 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Objective To observe the effect of Yangxueqingnao granules on c-Fos protein expression in trigeminal nucleus caudalis (TNC) of nitroglycerin-induced migraine rats.
Xiao-feng LEI +3 more
doaj
A mouse model to study inducible oncogene cooperation in vivo [PDF]
, 2012 The current model for cancer development envisions cells under going a series of genetic mutations and/or alterations which result in their inability to respond normally to intracellular and extracellular signals that control proliferation ...
Modica, Teresa Maria Elisa
core +1 more source
Studies of the Transcriptional Control of the Human c-fos Proto-Oncogene [PDF]
, 1989 The c-fos gene is the cellular counterpart of the transforming genes of several retroviruses. Its transcription and expression is increased in many types of different cells following extra-cellular stimuli, and this increase is both rapid and transient ...
Morgan, Iain Matthew
core
Asia-Pacific Journal of Clinical Oncology, EarlyView.ABSTRACT Background Globally, gastric cancer (GC) ranks as the fourth most deadly and fifth most prevalent kind of cancer. Appropriate treatment methods, precise etiology, and molecular processes of GC are still unclear. Methods In silico and quantitative real‐time reverse transcription polymerase chain reaction (qRT‐PCR)‐based expression of miRNA‐27b ...
Yang Dehuo, Wang Ying, Cao Lin
wiley +1 more source
The Platelet-derived Growth Factor Controls c-myc Expression through a JNK- and AP-1-dependent Signaling Pathway * [PDF]
, 2003 Pro-inflammatory cytokines, environmental stresses, as well as receptor tyrosine kinases regulate the activity of JNK. In turn, JNK phosphorylates Jun members of the AP-1 family of transcription factors, thereby controlling processes as different as cell
Annunziata Catania +9 more
core +2 more sources
MEGADOCK-Web-Mito: human mitochondrial protein-protein interaction prediction database [PDF]
arXiv, 2021 Mitochondrial diseases are largely caused by dysfunction in mitochondrial proteins. However, annotations of human mitochondrial proteins are scattered across various public databases and individual studies. To facilitate research aimed at elucidating mitochondrial functions, we constructed the MEGADOCK-Web-Mito database as a protein-protein interaction
arxiv
The universal role of adaptive transcription in health and disease
The FEBS Journal, EarlyView.Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley +1 more source
Physiological Signaling and Structure of the HGF Receptor MET [PDF]
, 2014 The \u201chepatocyte growth factor\u201d also known as \u201cscatter factor\u201d, is a multifunctional cytokine with the peculiar ability of simultaneously triggering epithelial cell proliferation, movement and survival.
Andrea Graziani, Gianluca Baldanzi
core +5 more sources