Results 81 to 90 of about 75,334 (151)

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu, Ziyuan Wang, Huirong Zhu, Yicun Han, Qing Ji   +4 more
wiley   +1 more source

Tumor-stroma interactions influence the response to PI3K targeted agents in preclinical models of colorectal cancer (CRC) [PDF]

, 2019
Introduction: One of the main obstacle to the successful development of therapeutic strategies remains the identification of biomarker underlying drug resistance. Recently, investigators have become more aware the role of the tumor microenvironment (TME)
Bazzichetto, Chiara
core  

Chrysin Exhibits Bone‐Protective Effects Through Osteoclastogenesis Inhibition: In Vitro and In Vivo Evaluation in RAW 264.7 Murine Macrophages and Sprague–Dawley Rats

Molecular Nutrition &Food Research, Volume 70, Issue 3, 13 February 2026.
The effects of chrysin, a plant‐derived compound, were investigated on osteoclast formation in cell culture and bone health parameters in Sprague–Dawley rats. Chrysin was shown to disrupt key osteoclast signaling pathways and inhibit osteoclast formation. Furthermore, chrysin moderately improved bone health parameters in the rats.
Caitlin Mason, Trevor T. Nyakudya, Abe E. Kasonga   +2 more
wiley   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

In vivo monitoring of a cAMP-stimulated DNA-binding activity [PDF]

, 1990
Boshart, Michael, Nitsch, Doris, Schlitz, Günther, Stewart, A. F., Weih, Falk   +4 more
core   +1 more source

SLC39A5 promotes the malignant progression of gastric cancer by activating BATF phosphorylation. [PDF]

J Biol Chem
Wang X, Li T, Xia M, Sun L, Wang X.
europepmc   +1 more source

Bibliometric analysis and core target identification of network pharmacology on neuroinflammation in central nervous system disorders: Trends, collaborations, and future directions. [PDF]

Neuroprotection
Zhang Y, Hou S, Li J, Wang W, Jia S, Wang X, Xia Y, Wang Y.   +7 more
europepmc   +1 more source

From advanced imaging to molecular insights: the state of the art in omics for axial spondyloarthritis. [PDF]

Ther Adv Musculoskelet Dis
Arias-de la Rosa I, Martín-Salazar JE, Cuesta-López L, López-Medina C C, Escudero-Contreras A, Collantes-Estévez E, Barbarroja N, Puche-Larrubia MÁ.   +7 more
europepmc   +1 more source

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors. [PDF]

Oncotarget
Ohana J, Sandler U, Weinberg BA, Liu S, Devary Y.   +4 more
europepmc   +1 more source

A novel mechanism by which c-MYC is aberrantly activated by epigenetic silencing of its antisense lncRNA in colon cancer. [PDF]

Front Genet
Hu X, Wei Y, Zhang M, Dou C, Wang L, Zaib G, Wu H, Guo W, Wang X, Chen S, Xu Q, Guo M, Cui H.   +12 more
europepmc   +1 more source