Algebraic and Topological Indices of Molecular Pathway Networks in Human Cancers [PDF]
Protein-protein interaction networks associated with diseases have gained prominence as an area of research. We investigate algebraic and topological indices for protein-protein interaction networks of 11 human cancers derived from the Kyoto Encyclopedia
Hinow, Peter +2 more
core
The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch +5 more
wiley +1 more source
Angiotensin II induces hypertrophy of human airway smooth muscle cells: expression of transcription factors and transforming growth factor-beta1 [PDF]
Increased smooth muscle mass due to hyperplasia and hypertrophy of airway smooth muscle (ASM) cells is a common feature in asthma. Angiotensin II (Ang II), a potent vasoconstrictor and mitogen for a wide variety of cells,
Jongste, J.C. (Johan) de +3 more
core
In vivo monitoring of a cAMP-stimulated DNA-binding activity [PDF]
Boshart, Michael +4 more
core +1 more source
Combinational Inhibition of the eIF4F Complex, AKT1, and EZH2 Enhances Anticancer Effects in BRAF<sup>V600E</sup> Mutant A375 Melanoma Cells. [PDF]
Miao Y, Hao F, Ki SH.
europepmc +1 more source
Candidate Key Proteins in Thalamo-Amygdala Signaling in Tinnitus: A Bioinformatics Study. [PDF]
Gross J, Knipper M, Mazurek B.
europepmc +1 more source
Rosa roxburghii Tratt. enhances fracture healing through multitarget regulation of osteogenesis and angiogenesis: Integrated network pharmacology and molecular docking analysis. [PDF]
Wu Z +6 more
europepmc +1 more source
Bioactive Metabolites from <i>Lactobacillus acidophilus</i>-Fermented Products Mitigate Carbon Tetrachloride-Induced Liver Injury: Biochemical and In Silico Insights. [PDF]
Islam MS +5 more
europepmc +1 more source
Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review). [PDF]
Wei M, Wang R, Qian J, Fang Q, Tao J.
europepmc +1 more source
The Small Molecule Compound Eupalinolide B Ameliorates Depressive Behaviors and Neuropathic Pain in Mice With Spared Nerve Injury: Integrating Network Pharmacology, Molecular Docking, Bioinformatics, Molecular Dynamics Simulation and Experimental Verification. [PDF]
Yang X, Jiang F, Wu Y, Chen K, Xiang H.
europepmc +1 more source

