Results 11 to 20 of about 59,281 (254)

Insertional Oncogenesis by Non-Acute Retroviruses: Implications for Gene Therapy

open access: yesViruses, 2011
Retroviruses cause cancers in a variety of animals and humans. Research on retroviruses has provided important insights into mechanisms of oncogenesis in humans, including the discovery of viral oncogenes and cellular proto-oncogenes. The subject of this
Hung Fan, Chassidy Johnson
doaj   +1 more source

Proto‐oncogenes and spermatogenesis [PDF]

open access: yesInternational Journal of Andrology, 1989
Expression des protooncogenes dans l'epithelium seminifere et au cours de la spermatogenese; implication dans la regulation du developpement des cellules ...
openaire   +2 more sources

Importância do vírus da leucemia felina na linfomagênese: Revisão

open access: yesPubvet, 2018
O vírus da Leucemia felina (FeLV) é um retrovírus oncogênico frequentemente relacionado ao linfoma em felinos domésticos. O principal mecanismo pelo qual o FeLV induz neoplasia é através da mutagênese insercional adquirida somaticamente, podendo o ...
Dayse Helena Lages da Silva   +3 more
doaj   +1 more source

Lung Cancer: A Literature Review

open access: yesJurnal Respirasi, 2023
Lung cancer is a cancer whose onset starts in the lungs where there is an abnormal cell growth that is very fast and uncontrolled. The abnormal cell growth is triggered by deoxyribonucleic acid (DNA) damage, including deletions in the DNA section ...
Yan Efrata Sembiring   +8 more
doaj   +1 more source

O PROTO-ONCOGENE RAS NO BÓCIO MULTINODULAR

open access: yesClinical and Biomedical Research, 2022
A transformação neoplásica resulta de uma série de alterações genéticas, envolvendo ativação de proto-oncogenes e inativação de genes supressores tumorais.
Lenara Golbert   +5 more
doaj  

Molecular Pathogenesis and Targeted Therapies in Well-Differentiated Thyroid Carcinoma [PDF]

open access: yesEndocrinology and Metabolism, 2014
Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-γ, may carry diagnostic and prognostic ...
Jung Guk Kim
doaj   +1 more source

A Review on the Molecular Pathology of Epithelial Thyroid Tumors

open access: yesمجله دانشکده پزشکی اصفهان, 2018
Epithelial thyroid tumors are all from the thyrocytes, the follicular epithelial cells of the thyroid. If these cells do not replicate the normal mechanisms of growth, cell division, and apoptosis, and enter to the uncontrolled growth phase, thyroid ...
Seyedeh Adeleh Razavi   +3 more
doaj   +1 more source

Dynamical Behaviour of a Time Delay Model of the ERK and STAT5 Interaction [PDF]

open access: yesBioautomation, 2007
In this paper we have done sensitive analysis of a time delay model which describes the ERK and STAT5 interaction. The results show that the type of the equilibrium point of the model can be a compound saddle-focus or a compound saddle-knot.
Kotev V.
doaj  

Detection of Mutations in Selected Proto-Oncogenes of Canine Lymphoma

open access: yesFolia Veterinaria, 2017
Lymphomas belong among the most frequently diagnosed tumours of the haematopoietic system in dogs. The clinical manifestations and genetic and molecular basis of canine lymphoma resembles those of human non-Hodgkin lymphoma and therefore it can serve as ...
Bóna G., Šiviková K.
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

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