Results 11 to 20 of about 325,026 (325)
Detection of Mutations in Selected Proto-Oncogenes of Canine Lymphoma
Folia Veterinaria, 2017 Lymphomas belong among the most frequently diagnosed tumours of the haematopoietic system in dogs. The clinical manifestations and genetic and molecular basis of canine lymphoma resembles those of human non-Hodgkin lymphoma and therefore it can serve as ...
Bóna G., Šiviková K.
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Oncogenes in immune cells as potential therapeutic targets
ImmunoTargets and Therapy, 2018 Gulnur K Zakiryanova,1 Sarah Wheeler,2 Michael R Shurin2 1Department Biophysics and Biomedicine, Faculty Biology and Biotechnology, Al-Farabi Kazakh National University, Almaty, Kazakhstan; 2Division of Clinical Immunopathology, Department of Pathology ...
Zakiryanova GK, Wheeler S, Shurin MR
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Polyploidy and Myc Proto-Oncogenes Promote Stress Adaptation via Epigenetic Plasticity and Gene Regulatory Network Rewiring. [PDF]
Int J Mol Sci, 2022 Polyploid cells demonstrate biological plasticity and stress adaptation in evolution; development; and pathologies, including cardiovascular diseases, neurodegeneration, and cancer.
Anatskaya OV, Vinogradov AE.
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Modulation of junction tension by tumor suppressors and proto-oncogenes regulates cell-cell contacts [PDF]
Development, 2016 International audienceTumor suppressors and proto-oncogenes play crucial roles in tissue proliferation. Furthermore, de-regulation of their functions is deleterious to tissue architecture and can result in the sorting of somatic rounded clones minimizing
Floris Bosveld +6 more
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Reviewing Oncogenes and Proto-Oncogenes
International Journal of Scientific Research in Science and Technology, 2021 This article is an examination of the Reviewing oncogenes and Proto-oncogenes The scientific development and subsequent “oncogenes and Proto-oncogenes” continues to influence the researchers all over the globe today.
Neha Batra +3 more
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Frontiers in Bioscience-Scholar, 2023 Background: Smoking is considered the single highest risk factor for lung cancer and has been suggested to be associated with accelerated somatic mutations in respiratory mucosa that lead to the development of lung cancer.
Amresh Kumar Mishra +2 more
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Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model. [PDF]
PLoS ONE, 2015 The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system.
Su Hwa Jang, Sohyun Lee, Hee Yong Chung
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Anais Brasileiros de Dermatologia, 2014 Costello syndrome (CS) is a rare genetic disorder, first described by Costello in 1971, caused by mutations in the HRAS proto-oncogene. Clinical findings include facial dysmorphism, skin disorders, cognitive impairment, cardiac and musculoskeletal ...
Isy Lima Peixoto +5 more
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ProtoPred: Advancing Oncological Research Through Identification of Proto-Oncogene Proteins
IEEE Access, 2021 Proto-oncogenes are the genes that have the potential to transform normal cells into cancer cells as a result of mutations. They usually contain encoding of proteins whose function is to inhibit cell differentiation, stimulate cell division, and prevent ...
Sharaf J. Malebary +2 more
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Insertional Oncogenesis by Non-Acute Retroviruses: Implications for Gene Therapy
Viruses, 2011 Retroviruses cause cancers in a variety of animals and humans. Research on retroviruses has provided important insights into mechanisms of oncogenesis in humans, including the discovery of viral oncogenes and cellular proto-oncogenes. The subject of this
Hung Fan, Chassidy Johnson
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