Results 11 to 20 of about 263,760 (324)
Dynamical Behaviour of a Time Delay Model of the ERK and STAT5 Interaction [PDF]
Bioautomation, 2007 In this paper we have done sensitive analysis of a time delay model which describes the ERK and STAT5 interaction. The results show that the type of the equilibrium point of the model can be a compound saddle-focus or a compound saddle-knot.
Kotev V.
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Genetic aspects of etiology and development of thyroid gland cancer [PDF]
Саратовский научно-медицинский журнал, 2012 Recent studies on thyroid gland cancer development and progression have identified new classes of tumor markers, proto-oncogenes, tumor-suppressing genes, cell receptor genes, identified genetic tumor-predisposing polymorphism and some other ...
Kovalenko Yu.V., Tolstokorov A.S.
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The expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers. [PDF]
Br J Cancer, 2015 BackgroundStudies of familial cancers have found that only a small subset of tissues are affected by inherited mutations in a given tumour suppressor gene (TSG) or proto-oncogene (POG), even though the mutation is present in all tissues.
Muir B, Nunney L.
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Frontiers in Bioscience-Scholar, 2023 Background: Smoking is considered the single highest risk factor for lung cancer and has been suggested to be associated with accelerated somatic mutations in respiratory mucosa that lead to the development of lung cancer.
Amresh Kumar Mishra +2 more
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Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model. [PDF]
PLoS ONE, 2015 The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system.
Su Hwa Jang, Sohyun Lee, Hee Yong Chung
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Anais Brasileiros de Dermatologia, 2014 Costello syndrome (CS) is a rare genetic disorder, first described by Costello in 1971, caused by mutations in the HRAS proto-oncogene. Clinical findings include facial dysmorphism, skin disorders, cognitive impairment, cardiac and musculoskeletal ...
Isy Lima Peixoto +5 more
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ProtoPred: Advancing Oncological Research Through Identification of Proto-Oncogene Proteins
IEEE Access, 2021 Proto-oncogenes are the genes that have the potential to transform normal cells into cancer cells as a result of mutations. They usually contain encoding of proteins whose function is to inhibit cell differentiation, stimulate cell division, and prevent ...
Sharaf J. Malebary +2 more
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Insertional Oncogenesis by Non-Acute Retroviruses: Implications for Gene Therapy
Viruses, 2011 Retroviruses cause cancers in a variety of animals and humans. Research on retroviruses has provided important insights into mechanisms of oncogenesis in humans, including the discovery of viral oncogenes and cellular proto-oncogenes. The subject of this
Hung Fan, Chassidy Johnson
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Detection of oncogene rearrangements in human non-Hodgkin's lymphomas. [PDF]
, 1992 Southern blot hybridization was used to detect the rearrangement and amplification of five proto-oncogenes (bcl-2, bcl-1, c-myc, c-myb and c-Ha-ras) and one tumor suppressor gene (RB-1) in 55 Japanese patients with non-Hodgkin's lymphoma; 16 with T-cell ...
Akagi, Tadaatsu +4 more
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